From Surf Wiki (app.surf) — the open knowledge base
Knife-edge scanning microscope
The Knife-Edge Scanning Microscope (KESM) was invented and patented in the late 1990s by Bruce McCormick at Texas A&M University. The microscope is intended to produce high-resolution data sets in order to reconstruct 3D cellular structures.
The machine is capable of handling tissue volumes of 1 to 100mm3, recording large volumes of tissue in a small amount of time (~7mm2s−1). The resolution and scanning speed of KESM is a novel method for imaging tissue at resolutions sufficient to reconstruct maps of cellular distribution and morphology. The technique preserves the alignment of serial sections accurately enough to reconstruct neuronal processes and microvasculature.
References
References
- Kathy Flores (2007). "Dr. Bruce H. McCormick" Texas A&M University. Retrieved 9 July 2008.
- B. H. McCormick, Development of the Brain Tissue Scanner, Technical Report, Brain Networks Laboratory, Department of Computer Science, Texas A&M University, College Station, Texas, 2002. [PDF]
- Knife-edge scanning microscope (KESM): http://research.cs.tamu.edu/bnl/kesm.html
This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.
Ask Mako anything about Knife-edge scanning microscope — get instant answers, deeper analysis, and related topics.
Research with MakoFree with your Surf account
Create a free account to save articles, ask Mako questions, and organize your research.
Sign up freeThis content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.
Report