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KCNG1

Protein-coding gene in the species Homo sapiens


Protein-coding gene in the species Homo sapiens

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.

References

References

  1. (Feb 1998). "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun.
  2. (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev.
  3. "Entrez Gene: KCNG1 potassium voltage-gated channel, subfamily G, member 1".
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