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HOT-17

Field	Value
Watchedfields	changed
verifiedrevid	415514475
image	HOT-17 chemical structure.svg
image_class	skin-invert-image
width	250px
routes_of_administration	Oral
class	Serotonergic psychedelic; Hallucinogen
ATC_prefix	None
metabolites	Possibly 2C-T-17
onset	0.5–1.5 hours
Peak: 3 hours
duration_of_action	12–18 hours
CAS_number_Ref
CAS_number	207740-40-7
PubChem	44350007
ChemSpiderID_Ref
ChemSpiderID	21106319
UNII_Ref
UNII	A9AD8C69LQ
ChEMBL_Ref
ChEMBL	127509
synonyms	4-sec-Butylthio-2,5-dimethoxy-N-hydroxyphenethylamine; 2,5-Dimethoxy-4-sec-butylthio-N-hydroxyphenethylamine; N-Hydroxy-2C-T-17; N-OH-2C-T-17
IUPAC_name	2-{4-[(butan-2-yl)sulfanyl]-2,5-dimethoxyphenyl}-N-hydroxyethan-1-amine
C	14	H=23	N=1	O=3	S=1
SMILES	CCC(C)SC1=C(C=C(C(=C1)OC)CCNO)OC
StdInChI_Ref
StdInChI	1S/C14H23NO3S/c1-5-10(2)19-14-9-12(17-3)11(6-7-15-16)8-13(14)18-4/h8-10,15-16H,5-7H2,1-4H3
StdInChIKey_Ref
StdInChIKey	BUKIXGXYEUJJHQ-UHFFFAOYSA-N

| Drugs.com =

Peak: 3 hours | elimination_half-life =

HOT-17, also known as 4-sec-butylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-17, is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-17. The drug is taken orally.

Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists HOT-17's dose range as 70 to 120mg orally and its duration as 12 to 18hours. The drug's onset is 30minutes to 1.5hours and peak effects occur after 3hours. HOT-17's properties are very similar to those of 2C-T-17, which has a dose of 60 to 100mg orally, a duration of 10 to 15hours, and an onset of 1hour with a time to peak of 3hours. HOT-17 may act as a prodrug of 2C-T-17.

The effects of HOT-17 have been reported to include "something going on upstairs", no sensory distortion, mild time distortion, feeling light and slightly floaty, walking feeling pleasant due to the lightness, and no body load, among others. It was described as producing "plus-two" and "plus-three" experiences on the Shulgin Rating Scale. The compound is said to have an "unbelievably grim taste—not bitter, but simply evil".

Interactions

Chemistry

Synthesis

The chemical synthesis of HOT-17 has been described.

Analogues

Analogues of HOT-17 include 2C-T-17, HOT-2 (N-hydroxy-2C-T-2), and HOT-7 (N-hydroxy-2C-T-7), among others.

History

HOT-17 was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).

Society and culture

Legal status

Canada

HOT-17 is a controlled substance in Canada under phenethylamine blanket-ban language.

References

{{CitePiHKAL https://www.erowid.org/library/books_online/pihkal/pihkal089.shtml
(2011). "[[The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds]]". [[Transform Press]].
"#81 FLEA".
"Controlled Drugs and Substances Act".

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

designer-prodrugs hot-x-(psychedelics) pihkal psychedelic-phenethylamines

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