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general/hla-b-alleles

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HLA-B45

Human leukocyte antigen serotype

Summary

Human leukocyte antigen serotype

Locuschr.6 6p21.31

HLA-B45 (B45) is an HLA-B serotype. The serotype identifies the B*45 gene-allele protein products of HLA-B.

B45 is a split antigen of the broad antigen B12, and is a sister type of B44. Gene products of 45 not 44

Serotype

Alleles link-out to IMGT/HLA Databease at EBI

Alleles

It was reported that a novel haplotype was found in Italian bone marrow donors. A2-CW1601-B45- DRB11101-DRB30301-DQA10102-DQB10502. This haplotype indicates possible very recent ancestry from Africa, with the Cw1601 and B45 components and also with the DR11-DQ5.2 component both extremely rare in Europe.

References

References

  1. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens.
  2. [http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]
  3. (April 1996). "A novel Italian haplotype predominates in HLA-B45-positive bone marrow donors: HLA-A2, CW1601, B45, DRB11101, DRB30301, DQA10102, DQB1*0502". Tissue Antigens.
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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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