From Surf Wiki (app.surf) — the open knowledge base

HLA-B44

Human leukocyte antigen serotype

Summary

Human leukocyte antigen serotype

Locus	chr.6 6p21.31

HLA-B44 (B44) is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B.

B44 is a split antigen of the broad antigen B12, and is a sister type of B45.

Serotype

Alleles link-out to IMGT/HLA Database at EBI

Alleles

Disease

HLA-B44 increases recurrent sinopulmonary infections. Protective effects: HLA-B44 appears to be protective against autoimmune lymphoproliferative syndrome in patients with C95 defect (ALPS type Ia). B44 may be a cofactor in ankylosing spondylitis

References

(2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens.
[http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]
(June 2006). "Increased frequency of HLA-B44 in recurrent sinopulmonary infections (RESPI)". Clin. Immunol..
(January 2006). "HLA B44 is associated with decreased severity of autoimmune lymphoproliferative syndrome in patients with CD95 defects (ALPS type Ia)". Clin. Immunol..
(November 1988). "HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA phenotype B27,B44". J. Rheumatol..

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

hla-b-alleles

Want to explore this topic further?

Ask Mako anything about HLA-B44 — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report