Surf Wiki
Save to docs
general/hla-b-alleles

From Surf Wiki (app.surf) — the open knowledge base

HLA-B38

Human leukocyte antigen serotype

Summary

Human leukocyte antigen serotype

Locuschr.6 6p21.31

HLA-B38 (B38) is an HLA-B serotype. The serotype identifies the B*38 allele products of the HLA-B gene-locus.

B38 is a split antigen of the broad antigen B16, and is a sister type of B39. The B3801 allele is more common in Eastern, Southern and Southeastern Europe, while the B3802 allele is more common in the Far East.

Serotype

Alleles link-out to IMGT/HLA Databease at EBI

Alleles

Ireland South0.8

Disease

A higher frequency of HLA-B38 was noted psoriatic arthritis patients with erythroderma. Psoriatic arthritis is linked to MICA and/or B39 in other peoples. In Pemphigus vulgaris a haplotype containing B38 was identified and found to be shared between Spanish and Jewish patients. Linkage studies indicate a factor in the HLA-class I region is more greatly associated, with HLA-B38 so far the only linked allele

Brazil0.7

References

References

  1. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens.
  2. [http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]
  3. (2003). "New allele frequency database". Tissue Antigens.
  4. (December 2006). "[Genetics in patients with psoriatic arthritis]". Orv Hetil.
  5. Eastmond CJ. (May 1994). "Psoriatic arthritis. Genetics and HLA antigens". Baillière's Clinical Rheumatology.
  6. (April 2004). "Common ancestral origin of pemphigus vulgaris in Jews and Spaniards: a study using microsatellite markers". Tissue Antigens.
  7. (August 2003). "Pemphigus vulgaris in Jewish patients is associated with HLA-A region genes: mapping by microsatellite markers". Hum. Immunol..
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

hla-b-alleles
Want to explore this topic further?

Ask Mako anything about HLA-B38 — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report