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general/hla-a-alleles

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HLA-A32

Human leukocyte antigen serotype


Summary

Human leukocyte antigen serotype

that result in 15 isoforms of HLA-A32. One isoform may be poorly expressed.

Distribution

A32 is most common around the Persian Gulf and the Mediterranean Basin. It has a consistent presence in Europe. The A32 frequencies in the more isolated (genetically) peoples of Europe suggests that the A32 rise in the Mediterranean may only be partially attributable to recent migrations from the middle eastern region. There is a node in southern Europe around the Ionian Sea in which specific, European, A32-haplotypes are elevated.

Haplotypes

Kalash2.9

A common A32 haplotype A3201-B5101 can be found in Oman, United Arab Emirates, SE Iran, Bulgaria, and Portugal. A second, A3201-B3501 can be in the Omani, UAE, and Portugal.

References

References

  1. (2006). "Identification of nine new HLA class I alleles in volunteers from the Singapore stem cell donor registries". Tissue Antigens.
  2. B*0705
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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