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Histone-arginine N-methyltransferase


FieldValue
NameHistone-arginine N-methyltransferase
EC_number2.1.1.125
CAS_number445295-80-7

Histone-arginine N-methyltransferase (, histone protein methylase I, nuclear protein (histone) N-methyltransferase, protein methylase I, S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:histone-arginine Nomega-methyltransferase. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + histone-arginine \rightleftharpoons S-adenosyl-L-homocysteine + histone-Nomega-methyl-arginine

The enzyme forms the Nomega-monomethyl- and Nomega,Nomega'-dimethyl.

References

References

  1. (January 1994). "Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine:histone-arginine N-methyltransferase". The Journal of Biological Chemistry.
  2. (June 1994). "Purification and characterization of S-adenosylmethionine-protein-arginine N-methyltransferase from rat liver". The Biochemical Journal.
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