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Haplogroup CT

Human Y chromosome DNA grouping indicating common ancestry

Human Y chromosome DNA grouping indicating common ancestry

FieldValue
nameCT
mapHaplogrupos ADN-Y África.PNG
origin-date~70,000 BP,Karafet et al. (2008) give "70,000", citing "68,500±6000 years" from Hammer and Zegura (2002). .
The split between CF and DE (which in the absence of a paragroup CT* is equivalent to the age of CT) has been dated to 70,000&ndash;75,000 years ago in [https://www.nature.com/nature/journal/v505/n7481/full/nature12736.html Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans], Nature 505, 87–91 (02 January 2014)</ref> ~100,000 BP,<ref name"A recent bottleneck of Y chromosome"{{cite journalvauthors = Kamin M, Saag L, Vincente M, et al.title = A recent bottleneck of Y chromosome diversity coincides with a global change in culture
journalGenome Researchvolume = 25
issue4
pages459–466
dateApril 2015pmid = 25770088pmc = 4381518
doi10.1101/gr.186684.114 }} or ~101,000 BP
origin-placeAfrica,{{cite journalvauthors = Kamin M, Saag L, Vincente M, et al.title = A recent bottleneck of Y chromosome diversity coincides with a global change in culture
journalGenome Researchvolume = 25
issue4
pages459–466
dateApril 2015pmid = 25770088pmc = 4381518
doi10.1101/gr.186684.114 }} possibly Northeast Africa
ancestorHaplogroup BT
descendantsHaplogroup CF, Haplogroup DE
mutationsP9.1, M168, M294, V9, V41, V54, V189, and V226

| origin-date = ~70,000 BP,Karafet et al. (2008) give "70,000", citing "68,500±6000 years" from Hammer and Zegura (2002). . The split between CF and DE (which in the absence of a paragroup CT* is equivalent to the age of CT) has been dated to 70,000–75,000 years ago in Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans, Nature 505, 87–91 (02 January 2014) ~100,000 BP,{{cite journal | vauthors = Kamin M, Saag L, Vincente M, et al. | title = A recent bottleneck of Y chromosome diversity coincides with a global change in culture | origin-place = Africa,{{cite journal | vauthors = Kamin M, Saag L, Vincente M, et al. | title = A recent bottleneck of Y chromosome diversity coincides with a global change in culture

Haplogroup CT is a human Y chromosome haplogroup. CT has two basal branches, CF and DE. DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.

Distribution

Men who carry the CT clade have Y chromosomes with the SNP mutation M168, along with P9.1 and M294. These mutations are present in all modern human male lineages except A and B-M60, which are both found almost exclusively in Africa.

The most recent common male line ancestor (TMRCA) of all CT men today probably predated the recent African origin of modern humans, a migration in which some of his descendants participated. He is therefore thought to have lived in Africa before this proposed migration. In keeping with the concept of "Y-chromosomal Adam" given to the patrilineal ancestor of all living humans, CT-M168 has therefore also been referred to in popularized accounts as being the lineage of "Eurasian Adam" or "Out of Africa Adam"; because, along with many African Y-lineages, all non-African Y-lineages descend from it.

No male in paragroup CT* has ever been discovered in modern populations. This means that all males carrying this haplogroup are also defined as being in one of the several major branch clades. All known surviving descendant lineages of CT are in one of two major subclades, CF and DE. In turn, DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.

According to a 2024 study, macrohaplogroup CT spread in the Sinai Peninsula after early humans left Africa and migrated to the Middle East about 130 kya.

Subclades

CF

Main article: Haplogroup CF (Y-DNA)

Haplogroup CF is a subclade of haplogroup CT.

DE

Main article: Haplogroup DE

Haplogroup DE is a subclade of haplogroup CT.

Phylogenetic trees

;Haplogroup CT (M168/PF1416)

  • CF (P143/PF2587, CTS3818/M3690/PF2668, CTS6376/M3711/PF2697) Shan people
    • C (M130/Page51/RPS4Y711, M216) * Asia, Oceania, and North America*
      • C1 F3393/Z1426
        • C1a CTS11043
          • C1a1 formerly C1 (M8, M105, M131) * Japan*
          • C1a2 Very low frequency in Western Eurasia (including Kostenki 38 000 years ago)
        • C1b
          • C1b1
            • C1b1a
              • C1b1a1 formerly C5 (M356) * South Asia, Central Asia, and Southwest Asia*
          • C1b2
            • C1b2a formerly C2 (M38) * Indonesia, New Guinea, Melanesia, Micronesia, and Polynesia*
            • C1b2b formerly C4 (M347) * Indigenous Australians*
      • C2 formerly C3 (M217, P44) Found throughout Eurasia and North America, but especially among Mongols, Kazakhs, Tungusic peoples, Paleosiberians, and Na-Dené-speaking peoples
    • F (M89, M213) Found throughout Eurasia, Oceania, and the Americas
      • F1 (P91, P104)
      • F2 (M427, M428)
      • F3 (P96)
      • F4 (M481)
    • GHIJK F1329/M3658/PF2622/YSC0001299, CTS2254/M3680/PF2657, FGC2045/Z12203 Throughout Eurasia; also The Americas; at low levels/among minorities in Africa and Oceania
      • G M201, P257 Primarily the Caucasus; also at low levels/among minorities in Europe, North Africa, South West Asia and Central Asia
      • HIJK Throughout Eurasia; also The Americas; at low levels/among minorities in Africa and Oceania
        • H M69, M370 * South Asia, Central Asia, and Southwest Asia*
        • IJK L15/S137, L16/S138 * Eurasia, North Africa, Oceania, the Americas and East Africa*
        • IJ M429/P125 * Europe, Western Asia, North Africa and East Africa*
          • I M170, M258, P19, P38, P212, U179 * Europe*
          • J 12f2.1, M304 * Europe, Western Asia, South Asia, North Africa and East Africa*
        • K M9 Found all over Eurasia; also significant in the Americas and Oceania; at lower levels in North Africa and East Africa
          • LT (K1) L298/P326
            • L M11, M20, M22, M61, M185, M295 * the Indian subcontinent*
            • T M70, M184/USP9Y+3178, M193, M272 (formerly K2) * Southwestern Asia, South Asia, North Africa, the Horn of Africa, the Chad Basin, and Southern Europe*
          • K2 M526 Eurasia, Oceania, The Americas, some indigenous Australians and some minorities in Africa
            • NO (K2a) M214 Reportedly found in small numbers of Buyi and Japanese males.
              • N M231 * Eastern Europe, North Asia, and East Asia*
              • O M175 * Oceania, Southeast Asia, and East Asia*
            • K2b formerly MPS P331 Eurasia, The Americas, Oceania and minorities in Africa
              • K2b1 formerly MS P397/P399 Melanesians, Micronesians, indigenous Australians and Polynesians.
                • M P256 Eastern Indonesia, Papua New Guinea, and Melanesia
                • S M230, P202, P204 (formerly K5) Eastern Indonesia, Papua New Guinea, and Melanesia
              • P (K2b2) 92R7, M45, M74/N12, P27.1/P207 Throughout Eurasia, The Americas and some minorities in Africa
                • Q M242 * The Americas and Eurasia*
                • R M207/UTY2, M306/S1 Europe, Near East, South Asia, Chad Basin, Canary Islands
            • K2c P261 Low levels in Bali
            • K2d P402/P403 Low levels in Java
            • K2e M147 Low levels in South Asia
  • Haplogroup DE (M1/YAP, M145/P205, M203/Page36, P144, P153, P165, P167, P183) Asia, Africa, Southern and Eastern Europe; also at low levels in Oceania
    • Haplogroup D (M174) Primarily Japan, Tibet and Andaman Islanders; also at low level/among minorities in East Asia, Central Asia, Micronesia and Melanesia
      • Haplogroup D1 (CTS11577) Mainly Tibet; minorities in Central Asia, East Asia, and South East Asia
        • Haplogroup D1a Z27276 East and Central Asia
          • D1a1 (M15) (ex-D1) Qiang people; also at low levels throughout East and Central Asia
          • Haplogroup D1a2 P99 (ex-D3) Tibet and Central Asia
        • Haplogroup D1b (ex-D2) (M64.1/Page44.1, M55, M57, M179/Page31, M359.1/P41.1, P37.1, P190, 12f2.2) Mainly Japan; also at lowel levels/among minorities in Korea, China, Micronesia and Melanesia
      • Haplogroup D2 L1366 (ex-D1a) Philippines
    • Haplogroup E (M40, M96) * Africa, Middle East, Southern and Eastern Europe*
      • Haplogroup E1 (P147) At high levels throughout Africa; at lower levels in the Middle East and Europe
        • Haplogroup E1a (formerly E1) (M132) Primarily Africa
        • Haplogroup E1b (P177/PF1939)
          • Haplogroup E1b1 (formerly E3) (P2, DYS391p)
            • Haplogroup E1b1a (V38)
            • Haplogroup E1b1a1 (formerly E3a) (M2) * West Africa, Central Africa, Southeast Africa and Southern Africa*
            • Haplogroup E1b1b (formerly E3b) (M215) * Horn of Africa (Ethiopians, Somalis, Eritrea), North Africa (Berbers, Arabs), the Middle East, Europe (esp. areas near the Mediterranean Sea)*
      • Haplogroup E2 (M75) East Africa

Sources

References

References

  1. (June 2019). "A Rare Deep-Rooting D0 African Y-chromosomal Haplogroup and its Implications for the Expansion of Modern Humans Out of Africa". Genetics.
  2. Underhill and Kivisild. (2007). "Use of Y Chromosome and Mitochondrial DNA Population Structure in Tracing Human Migrations". Annu. Rev. Genet..
  3. Stone, Linda. (2007). "Genes, Culture, and Human Evolution". Wiley.
  4. Underhill and Kivisild. (2007). "Use of Y Chromosome and Mitochondrial DNA Population Structure in Tracing Human Migrations". Annu. Rev. Genet..
  5. 1-4051-5089-0, page 187
  6. 0-19-530675-9, {{ISBN. 978-0-19-530675-0
  7. (2008). "New Binary Polymorphisms Reshape and Increase Resolution of the Human Y-Chromosomal Haplogroup Tree". Genome Research.
  8. Cabrera, Vicente M.. (2024). "Early male and female footprints of modern humans across Eurasia and Australasia". Medical Research Archives.
  9. Pereira et al. (2010), [https://www.nature.com/ejhg/journal/v18/n8/abs/ejhg201021a.html Linking the sub-Saharan and West Eurasian gene pools: maternal and paternal heritage of the Tuareg nomads from the African Sahel], European Journal of Human Genetics (2010) 18, 915–923; {{doi. 10.1038/ejhg.2010.21
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