Haplogroup A (mtDNA)

Origin

Haplogroup A is believed to have arisen in Asia some 30,000–50,000 years BC. Its ancestral haplogroup was Haplogroup N. However, the extant diversity of mitochondrial genomes that belong to Haplogroup A is low relative to the degree of divergence from its nearest outgroups in haplogroup N, which suggests that extant members of Haplogroup A might be descended from a population that has emerged from a bottleneck approximately 20,000 years ago.

Its highest frequencies are among Native Americans, its largest overall population is in East Asia, and its greatest variety (which suggests its origin point) is in East Asia. Thus, it might have originated in and spread from the Far East.

Distribution

Its subclade A2 shares a T16362C mutation with subclades A1 (found in Japan, Tashkurgan, Veliky Novgorod, Mongols, and Altaians), A6 (found in Tibet and in the Yangtze River basin), A12'23 (found in Siberia and among Uralic and Turkic peoples), A13'14 (found in southern Siberia, Xinjiang, Ladakh, China, Yunnan, Thailand, and Vietnam), A15 (found in China, Naxi, Uyghur, Japan, and among the Sherpa of Tibet and Nepal), A16 (found in Uyghur, Buryat, Turkey), A17 (found in China, Miao, Yi, Tibet, Ladakh, Kyrgyz, Thailand, and Vietnam), A18 (found in China), A19 (found in China), A20 (found among Han Chinese and in Japan), A21 (found in Tibet and in Jammu and Kashmir), A22 (found in China), A24 (found in Beijing and West Bohemia), A25 (found in Japan and Yakutia), and A26 (found in Denmark). A2 is found in Chukotko–Kamchatka and is also one of five mtDNA haplogroups found in the indigenous peoples of the Americas, the others being B, C, D, and X.

Haplogroup A2 is the most common haplogroup among the Inuit, Na-Dene, and many Amerind ethnic groups of North and Central America. Lineages belonging to haplogroup A2 also comprise the majority of the mtDNA pool of the Inuit and their neighbors, the Chukchis, in northeasternmost Siberia.

Other branches of haplogroup A are less frequent but widespread among other populations of Asia. Haplogroup A5 is rather limited to populations from Korea and Japan southward, though it has been detected as singletons in a pair of large samples of Khamnigans (1/99 = 1.0%) and Buryats (1/295 = 0.3%) from the Buryat Republic.

In Asia, A(xA2) is especially frequent in Tibeto-Burman-speaking populations of Southwest China, such as Tibetans (6/65 = 9.2%, 25/216 = 11.6%, 11/73 = 15.1%). Approximately 7% to 15% of Koreans belong to haplogroup A. Approximately 5% to 12% of the Japanese belong to haplogroup A (including A4, A5, and A(xA4, A5)). Approximately 4% to 13% of Mongols belong to haplogroup A, almost all of whom are contained within the A4 subclade (2/47 = 4.3% Mongolians from Ulan Bator in haplogroup A4, 4/48 = 8.3% Mongols from New Barag Left Banner in haplogroup A(xA5), 6/47 = 12.8% Mongolians from Ulan Bator in haplogroup A4). Approximately 3% to 9% of Chinese people belong to haplogroup A. Haplogroup A also has been found in Vietnamese (2/42 = 4.8%, including one A4 and one A5(xA5a)). Approximately 4% (3/71) of Tatars from Aznakayevo, 3% (4/126) of Tatars from Buinsk, and 2% of Turkish people belong to haplogroup A. Haplogroup A4 has been found in 2.4% (2/82) of a sample of Persians from eastern Iran and in 2.3% (1/44) of a sample of Tajiks from Tajikistan. Haplogroup A is not found among Austronesians. In Nepalese population except Sherpa, haplogroup A was mirrored by its clades, A27, A14 and A17, of which A27 was the most abundant clade in Newar (3.99%). Newly defined clade A27 only discerned so far in Newar and Nepali-mix coalesce at ~ 8.4 Kya suggesting their ancient origin and potentially in situ differentiation in Nepal.

Subclades

Tree

This phylogenetic tree of haplogroup A subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.

• A
  • A(xA5, A8, A10) — China (Han from Wuhan), Buryat (Inner Mongolia)
    • A+T152C!+T16362C — Uyghur, Korea, Japan, Vietnam (Hmong from Lao Cai Province, Kinh from Hanoi, Cờ Lao)
      • A1 [TMRCA 12,800 (95% CI 6,500 ↔ 22,700) ybp]
        • A1* — Japan, Korea
        • A1a [TMRCA 7,500 (95% CI 4,500 ↔ 11,800) ybp]
          • A1a* — Japan (Aichi), Sarikoli (Tashkurgan), USA, England
          • A1a1 [TMRCA 5,000 (95% CI 2,200 ↔ 9,800) ybp]
            • A1a1* — Buryat, Altai Kizhi
            • A1a1a — Buryat, Mongol (Inner Mongolia) [TMRCA 1,050 (95% CI 75 ↔ 5,500) ybp]
          • A1a2 — Russia (Bashkortostan, Velikij Novgorod), Iran (Turkmen) [TMRCA 1,950 (95% CI 100 ↔ 10,500) ybp]
          • A1a3 — Greece (Ioannina), United States (West Virginia) [TMRCA 1,150 (95% CI 75 ↔ 6,000) ybp]
      • A2 — Ache, Waiwai, Zoro, Surui, Waiapi, Poturujara, Kayapo, Katuena, Guarani, Arsario, Cayapa, Dogrib, ancient Canada, USA (Pennsylvania, California), Mexico (Zapotec), Cuba, Dominican Republic, Colombia, Venezuela, Ecuador, Peru, Argentina [TMRCA 10,600 (95% CI 9,600 ↔ 11,700) ybp]
        • A2a — Eskimo (Greenland, Chukotka), Chukchi
          • A2a1 — Inuit (Canada), Selkup
          • A2a2 — Eskimo (Chukotka), Chukchi
          • A2a3 — Eskimo (Greenland, Canada, Chukotka), Chukchi
          • A2a4 — USA (New Mexico, Arizona), Mexico (Chihuahua)
          • A2a5 — Apache, USA (California, Arizona, New Mexico, Texas), Canada (Cree, Shuswap)
        • A2b — Chukchi
          • A2b1 — Chukchi, Koryak, Eskimo (Chukotka, Canada, Greenland)
        • A2c
        • A2d — USA (Mexican, Hispanic)
          • A2d1 — USA (Mexican)
            • A2d1a — USA (Hispanic)
          • A2d2 — USA (Hispanic)
        • A2e'ao
          • A2e
          • A2ao
            • A2ao1
        • A2f
          • A2f1 — Newfoundland
            • A2f1a — Canada, USA (Native American)
          • A2f2 — USA (Mexican, Hispanic), Mexico
          • A2f3 — USA (Mexican, Hispanic)
        • A2g — USA (Mexican, Hispanic), Mexico, Iberian Peninsula
          • A2g1 — USA (Mexican, Hispanic), Latin America
        • A2h — Colombia (Cocama of Amazonas, Arhuaco), Yanomama, Kogui
          • A2h1 — USA (Mexican, Hispanic), Mexico, Latin America
        • A2i — USA (Hispanic, etc.), Canada (Ojibwa, Prince Edward Island, Pabos in Quebec)
        • A2j — USA (Hispanic)
          • A2j1 — USA (Hispanic)
        • A2k — USA (Puerto Rico)
          • A2k1 — Ecuador, Wayuu, Mexico
            • A2k1a — Venezuela, Colombia (Pasto of Putumayo), USA (Hispanic)
        • A2l'm'n'o'ai'aj
          • A2l
          • A2m
          • A2n — Canada
          • A2o
          • A2ai
          • A2aj
        • A2p'am
          • A2p
            • A2p1
            • A2p2
          • A2am — USA (Puerto Rico, Hispanic), Venezuela. One ancient DNA found in Curaçao, in a Dabajuroid (Caquetio) site dating 1160-1500 CE.
        • A2q
          • A2q1
        • A2r — USA (Hispanic, Mexican), Cuba
          • A2r1 — Mexico, USA (Mexican)
        • A2s
        • A2t — USA (Mexican)
        • A2u
          • A2u1
          • A2u2
        • A2v
          • A2v1 — USA (Mexican, Hispanic), Mexico (La Mixteca)
            • A2v1a — Guatemala, USA (Mexican)
            • A2v1b — Mexico
            • A2v1i — USA, Mexico (Mexican, Hispanic)
        • A2w — Colombia (Kogi, Guambiano of Putumayo), Arsario, USA (Mexican, Hispanic)
          • A2w1 — Mexico, Cayman Islands, Guatemala (La Tinta), Panama (Guaymi), Colombia
        • A2x
        • A2y
        • A2z — USA (Hispanic, Puerto Rico)
        • A2aa
        • A2ab - Brazil (PE, MT), Paraguay, Argentina
        • A2ac
          • A2ac1
        • A2ad
          • A2ad1
          • A2ad2
        • A2ae
        • A2af
          • A2af1
            • A2af1a
              • A2af1a1
              • A2af1a2
            • A2af1b
              • A2af1b1
                • A2af1b1a
                • A2af1b1b
              • A2af1b2
          • A2af2
        • A2ag
        • A2ah
        • A2ak
        • A2al
        • A2an
        • A2ap
        • A2aq
      • A6 [TMRCA 12,000 (95% CI 8,600 ↔ 16,100) ybp]
        • A6* — Deng, Korea
        • A6a — China [TMRCA 9,600 (95% CI 5,500 ↔ 15,500) ybp]
          • A6a* — Han Chinese (Wuhan, etc.)
          • A6a1 — Tujia
        • A6b — Tibet [TMRCA 5,000 (95% CI 2,700 ↔ 8,300) ybp]
          • A6b* — Tibet (Chamdo, Ladakh)
          • A6b1 — Tibet (Sherpa)
        • A6c — Tibet (Lhoba, Monpa)
      • A12'23 — Austria, Romania, Poland, Russia, possibly found among Udmurts and Komis
        • A12 — Czech Republic, Germany [TMRCA 11,800 (95% CI 6,500 ↔ 19,700) ybp]
          • A12a — Ireland, UK, New Zealand, USA, Nenets, Selkup [TMRCA 4,700 (95% CI 2,700 ↔ 7,600) ybp]
            • A12a* — Mansi, Yakut (Vilyuy River basin),
            • A12a1 — Kyordyughen Site (Ymyiakhtakh Culture, Yakutia), Hungary (Debrecen) [TMRCA 2,800 (95% CI 1,450 ↔ 4,900) ybp]
            • A12a2 — Evenk (Krasnoyarsk Krai, Stony Tunguska River basin) [TMRCA 1,250 (95% CI 100 ↔ 6,600) ybp]
          • A12b — Buryat, Karos-Eperjesszög (Hungarian conqueror period) [TMRCA 3,000 (95% CI 425 ↔ 10,700) ybp]
        • A23 — Mongol (Inner Mongolia), Buryat, Ket, Qashqai (Iran), ancient Scythian (Chylenski) [TMRCA 6,200 (95% CI 3,300 ↔ 10,600) ybp]
      • A13'14 — Russia (Buryat, Khamnigan), China (Shiyan, Tu, Uyghur, etc.), Ladakh, Thailand, Vietnam (Mang), Korea, Japan, Paraguay (Alto Parana), Ireland
        • A13
          • A13a — Thailand (Khon Mueang from Chiang Rai Province and Lampang Province), China
          • A13b
            • A13b1 — Uyghur, Taiwan
            • A13b2 — China (Lahu, etc.), Thailand (Red Lahu from Mae Hong Son Province), Vietnam (Phù Lá)
              • A13b2a — China (Naxi), Thailand (Lisu from Mae Hong Son Province)
        • A14 — Russia (Altai Kizhi, etc.), Kyrgyz (Artux), Uyghur, China, Han Chinese (Denver), Taiwan, Thailand (Lawa from Chiang Mai Province, Mon from Lopburi Province), Vietnam (Pa Then)
      • A15 — Uyghur
        • A15a — China (Han in Beijing, Lanzhou, etc.), Tibet (Tingri), Uyghur, Japan
        • A15b — China, Japan (Ehime)
        • A15c — China
          • A15c1 — Naxi, Tibet (Sherpa), Nepal (Sherpa)
      • A16 — Buryat, Uyghur, Turk
      • A17 — China (Han from Beijing, Lanzhou, etc.), Miao, Yi, Tibet (Lhoba, Monpa, Tingri), Ladakh, Kyrgyz (Tashkurgan), Thailand (Lawa from Chiang Mai Province and Mae Hong Son Province, Blang from Chiang Rai Province, Mon from Ratchaburi Province), Vietnam (Phù Lá, Hà Nhì)
      • A18 — Japan, China (Han from Fujian, Han from Beijing, Han from Lanzhou), Romania
      • A19 — China (Han from Beijing, etc.)
      • A20 — Japan, Han Chinese (Denver)
      • A21 — Tibet (Sherpa, Deng, etc.), Jammu and Kashmir
      • A22 — China, Han Chinese (Denver)
      • A24 — China (Han in Beijing), Turkey, Czech Republic (West Bohemia)
      • A25 — Japan (Chiba), China, Yakut (Vilyuy River basin)
      • A26 — Denmark
    • A3 — Japan (Tokyo, etc.), Korea, USA [TMRCA 6,800 (95% CI 3,200 ↔ 12,600) ybp]
      • A3a — Japan (Aichi, etc.) [TMRCA 4,300 (95% CI 1,400 ↔ 9,800) ybp]
    • A7 [TMRCA 8,800 (95% CI 5,400 ↔ 13,500) ybp]
      • A7* — China
      • A7a — Tibet [TMRCA 7,000 (95% CI 3,900 ↔ 11,700) ybp]
        • A7a* — Lhoba
        • A7a1 — Lhoba
        • A7a2 — Lhoba, Monpa
      • A7b — Japan (Tokyo, etc.) [TMRCA 6,300 (95% CI 2,100 ↔ 14,700) ybp]
    • A9
    • A11 — Nepal, Korea, Russia [TMRCA 14,500 (95% CI 9,700 ↔ 20,800) ybp]
      • A11a — Tibet (Lhasa, Nyingchi, Tingri, Sherpa, Lhoba, etc.), Ladakh
      • A11b — Tibet (Tingri, Chamdo, etc.), Naxi, Han (Yunnan)
  • A5 — China (incl. Hong Kong), Japan [TMRCA 16,200 (95% CI 11,100 ↔ 22,800) ybp]
    • A5a — Japan (Tokyo, Aichi, etc.), Korea, China [TMRCA 5,500 (95% CI 3,800 ↔ 7,600) ybp]
      • A5a1 — Korea
        • A5a1a — Japan (Tokyo, etc.), Korea
          • A5a1a1 — Japan (Tokyo, Chiba, Aichi, etc.), Korea
            • A5a1a1a — Japan (Tokyo, etc.)
            • A5a1a1b — Japan (Tokyo, Chiba, etc.), Korea
          • A5a1a2 — Japan, Korea
            • A5a1a2a — Japan (Aichi)
        • A5a1b — Japan (Tokyo, Aichi)
      • A5a2 — Japan (Tokyo, Aichi, etc.)
      • A5a3
        • A5a3* — Korea, USA (African American)
        • A5a3a
          • A5a3a* — Japan (Tokyo)
          • A5a3a1 — Japan (Tokyo, Aichi, etc.)
      • A5a4 — Japan
      • A5a5 — Japan, South Korea (Seoul), Uyghur
    • A5b — China (Tujia, Hui, etc.) [TMRCA 12,800 ybp (95% CI 8,400 ↔ 18,800) ybp]
      • A5b1 — China (Han from Beijing, etc.), Japan, Korea, Uyghur, Thailand, Vietnam (Tay), Singapore [TMRCA 8,600 (95% CI 6,600 ↔ 11,100) ybp]
        • A5b1* — Uyghur
        • A5b1a — Japan (Tokyo, etc.), Korea [TMRCA 6,700 (95% CI 3,700 ↔ 11,300) ybp]
        • A5b1b — China (Han from Fujian, Miao, etc.), Uyghur, Korea [TMRCA 7,300 (95% CI 5,600 ↔ 9,400) ybp]
          • A5b1b* — Han Chinese
          • A5b1b1
            • A5b1b1* — Miao
            • A5b1b1a — China
            • A5b1b1b — China
          • A5b1b2 — Uyghur
        • A5b1c — Han Chinese (Denver) [TMRCA 7,600 (95% CI 3,100 ↔ 15,500) ybp]
          • A5b1c1 — Taiwan (Hakka, Bunun, Paiwan) [TMRCA 5,400 (95% CI 1,800 ↔ 12,600) ybp]
        • A5b1d [TMRCA 7,300 (95% CI 3,700 ↔ 13,000) ybp]
          • A5b1d* — China
          • A5b1d1 — Siamese (Central Thailand), Tay (Vietnam)
      • A5b2 — China (Tujia, etc.)
    • A5c — Japan (Aichi, etc.), Korea, Khamnigan, Buryat, Barghut [TMRCA 8,200 (95% CI 4,800 ↔ 13,000) ybp]
      • A5c1 — Japan (Tokyo, Chiba, Aichi, etc.)
  • A8 — Uyghur [TMRCA 14,000 (95% CI 9,500 ↔ 19,800) ybp]
    • A8a — Okunev culture, Ket, Selkup, Pakistan, Poland, Italy [TMRCA 11,000 (95% CI 8,000 ↔ 14,800) ybp]
      • A8a* — Han Chinese (Guizhou), Korean
      • A8a1 — Hungary, Albania [TMRCA 5,500 (95% CI 3,000 ↔ 9,200) ybp]
        • A8a1* — Uyghur, Poland (Podhale), USA (Louisiana)
        • A8a1a — Yakut, Uyghur, Buryat
      • A8a2
        • A8a2a — Kets (Kellog, etc.), Tofalar (Alygdzher) [TMRCA 2,200 (95% CI 125 ↔ 12,000) ybp]
        • A8a2b — Tuvan (Bay-Tal), Poland
    • A8b — Koryak [TMRCA 1,050 (95% CI 75 ↔ 5,600) ybp]
  • A10 — China (Uyghur), Afghanistan (Hazara, Uzbek), Russia (Mansi, Volga Tatars, etc.), France, Canada, New York [TMRCA 9,200 (95% CI 4,900 ↔ 15,600) ybp]

Table of Frequencies of MtDNA Haplogroup A

Popular culture

The mummy "Juanita" of Peru, also called the "Ice Maiden", has been shown to belong to mitochondrial haplogroup A.

In his popular book The Seven Daughters of Eve, Bryan Sykes named the originator of this mtDNA haplogroup Aiyana.

Eva Longoria, an American actress of Mexican descent, belongs to Haplogroup A2. Michelle Rodriguez, an American actress with a Dominican mother, is likewise in A2.

References

References

1. (April 2012). "A "Copernican" reassessment of the human mitochondrial DNA tree from its root". Am J Hum Genet.
2. (2008). "Mitochondrial Population Genomics Supports a Single Pre-Clovis Origin with a Coastal Route for the Peopling of the Americas". American Journal of Human Genetics.
3. Tanaka, Masashi. (2004). "Mitochondrial Genome Variation in Eastern Asia and the Peopling of Japan". Genome Research.
4. (9 May 2008). "Mitochondrial Genome Diversity in Arctic Siberians, with Particular Reference to the Evolutionary History of Beringia and Pleistocenic Peopling of the Americas". The American Journal of Human Genetics.
5. (October 2008). "Northwest Siberian Khanty and Mansi in the junction of West and East Eurasian gene pools as revealed by uniparental markers". Eur J Hum Genet.
6. (March 2007). "Mitochondrial Haplogroup N9a Confers Resistance against Type 2 Diabetes in Asians". The American Journal of Human Genetics.
7. (May 2012). "Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans". Proc Natl Acad Sci U S A.
8. (November 2007). "Phylogeographic analysis of mitochondrial DNA in northern Asian populations". Am J Hum Genet.
9. (2009). "The peopling of Korea revealed by analyses of mitochondrial DNA and Y-chromosomal markers". PLOS ONE.
10. (October 2003). "Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China". Hum Genet.
11. (January 2005). "Multiplex amplified product-length polymorphism analysis of 36 mitochondrial single-nucleotide polymorphisms for haplogrouping of East Asian populations". Electrophoresis.
12. (September 2007). "Utility of haplogroup determination for forensic mtDNA analysis in the Japanese population". Legal Medicine.
13. (6 October 2011). "Major Population Expansion of East Asians Began before Neolithic Time: Evidence of mtDNA Genomes". PLOS ONE.
14. (1 October 2010). "Mitogenomic Diversity in Tatars from the Volga-Ural Region of Russia". Molecular Biology and Evolution.
15. (2008). "Culture creates genetic structure in the Caucasus: Autosomal, mitochondrial, and Y-chromosomal variation in Daghestan". BMC Genetics.
16. (January 2010). "Philippine mitochondrial DNA diversity: a populated viaduct between Taiwan and Indonesia?". Mol Biol Evol.
17. (2022-10-15). "The matrilineal ancestry of Nepali populations". Human Genetics.
18. van Oven, Mannis. (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation.
19. (October 2017). "Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements". Sci Rep.
20. "YFull MTree 1.01.5539".
21. (February 2021). "A genetic history of the pre-contact Caribbean". Nature.
22. "A2ab MTree".
23. (September 2018). "Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations". Genome Biol.
24. (April 2017). "Sex-specific genetic diversity is shaped by cultural factors in Inner Asian human populations". Am J Phys Anthropol.
25. (June 2018). "Investigating Holocene human population history in North Asia using ancient mitogenomes". Sci Rep.
26. (2017). "Revising mtDNA haplotypes of the ancient Hungarian conquerors with next generation sequencing". PLOS ONE.
27. (2014). "Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences". Investigative Genetics.
28. (2013). "Complete mitochondrial DNA diversity in Iranians". PLOS ONE.
29. (March 2019). "The maternal inheritance of Alto Paraná revealed by full mitogenome sequences". Forensic Sci Int Genet.
30. (January 2017). "Complete mitochondrial genomes of Thai and Lao populations indicate an ancient origin of Austroasiatic groups and demic diffusion in the spread of Tai-Kadai languages". Hum Genet.
31. (November 2020). "Cultural variation impacts paternal and maternal genetic lineages of the Hmong-Mien and Sino-Tibetan groups from Thailand". Eur J Hum Genet.
32. (May 2021). "New insights into the fine-scale history of western-eastern admixture of the northwestern Chinese population in the Hexi Corridor via genome-wide genetic legacy". Mol Genet Genomics.
33. [https://www.familytreedna.com/public/mt-dna-haplotree/M MtDNA Haplotree at Family Tree DNA]
34. (July 2006). "Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations". Hum Mol Genet.
35. (January 2022). "The frequency of the known mitochondrial variants associated with drug-induced toxicity in a Korean population". BMC Med Genomics.
36. (November 2006). "East Asian mtDNA haplogroup determination in Koreans: haplogroup-level coding region SNP analysis and subhaplogroup-level control region sequence analysis". Electrophoresis.
37. (November 1996). "Distribution of four founding mtDNA haplogroups among Native North Americans". Am J Phys Anthropol.
38. (2006). "Genetics, Linguistics, and Prehistoric Migrations: An Analysis of California Indian MitochondrialDNA Lineages". Journal of California and Great Basin Anthropology.
39. (2004). "Ancient DNA — Modern Connections: Results of Mitochondrial DNA Analyses from Monterey County, California". Pacific Coast Archaeological Society Quarterly.
40. Kang, Longli. (2016-08-08). "MtDNA analysis reveals enriched pathogenic mutations in Tibetan highlanders". Scientific Reports.
41. Li, Yu-Chun. (2019-08-01). "River Valleys Shaped the Maternal Genetic Landscape of Han Chinese". Molecular Biology and Evolution.
42. Irene Cardinali, Martin Bodner. (2022). "Mitochondrial DNA Footprints from Western Eurasia in Modern Mongolia". Frontiers in Genetics.
43. (2013-12-12). "Investigating the Prehistory of Tungusic Peoples of Siberia and the Amur-Ussuri Region with Complete mtDNA Genome Sequences and Y-chromosomal Markers". PLOS ONE.
44. (2023-11-14). "Whole mitochondrial genome analysis in highland Tibetans: further matrilineal genetic structure exploration". Frontiers in Genetics.
45. "YFull {{!}} Mitochondrial genome variation in eastern Asia and the peopling of Japan".
46. (January 28, 2021). "Mitochondrial genome diversity on the Central Siberian Plateau with particular reference to the prehistory of northernmost Eurasia". PLOS ONE.
47. (2022-05-18). "Whole mitochondrial genome analysis of the Daur ethnic minority from Hulunbuir in the Inner Mongolia Autonomous Region of China". BMC Ecology and Evolution.
48. (2009). "Mitochondrial DNA haplogrouping of the Okhotsk people based on analysis of ancient DNA: an intermediate of gene flow from the continental Sakhalin people to the Ainu". Anthropological Science.
49. Pischedda, S.. (2017-10-03). "Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements". Scientific Reports.
50. "The peopling of the Americas: Genetic ancestry influences health". Scientific American.
51. "First Americans Endured 20,000-Year Layover — Jennifer Viegas, Discovery News".
52. Gates Jr., Henry Louis. (2010). "Faces of America: How 12 Extraordinary People Discovered Their Pasts". New York University Press.
53. Gates Jr., Henry Louis. (2015). "Finding Your Roots: The Official Companion to the PBS Series". The University of North Carolina Press.
54. (2022-11-29). "Kazak mitochondrial genomes provide insights into the human population history of Central Eurasia". PLOS ONE.