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Halogenoderma

Field	Value
name	Halogenoderma
field	Dermatology

Halogenodermas are skin eruptions that result after exposure to halogen-containing drugs or substances. This may last several weeks after drug use is discontinued. This is because of the slow elimination rate of iodides and bromides. Fluoroderma is a particular type of halogenoderma which is caused by fluoride. Fluoride is present in oral hygiene products such as toothpastes and mouth washes, hence this type of acne is seen mostly around the mouth and jawline. Acute fluoroderma has been observed in patients exposed to anaesthetics containing fluoride such as sevoflurane.

Signs and symptoms

The most common presentation of halogenoderma is pustules or papulopustular lesions, which are often found on the face, neck, back, and limbs. In some cases, halogenoderma manifests as large vegetating lesions as opposed to pustular eruption.

Cause

Exposure to halogens, such as iodide and bromide (also known as iododerma and bromoderma, respectively), can cause halogenoderma.

Mechanism

It is still unclear what causes halogenoderma specifically. It's thought that a type 2 delayed hypersensitivity reaction is what causes it.

Treatment

Iodide and bromide-containing substances should be avoided when treating halogenoderma. Lesions typically go away on their own four to six weeks after iodide or bromide intake is stopped. It is possible to use systemic corticosteroids to help these lesions heal more quickly.

References

Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
(1 July 2011). "Fluoroderma after exposure to sevoflurane". British Journal of Anaesthesia.
(2011). "Thyroid Protection Gone Awry: Iododerma Following Potassium Iodide Administration Prior to Metaiodobenzylguanidine Scintigraphy". Mary Ann Liebert Inc.
(October 8, 2019). "Diffuse vegetating bromoderma". Wiley.
(November 23, 2022). "Halogenoderma: A Case Report and Review of the Literature". Cureus, Inc..
(2018). "An acneiform eruption secondary to iododerma". Elsevier BV.
(April 8, 2013). "Iododerma following topical povidone-iodine application". Informa UK Limited.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

drug-eruptions

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