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Gravindex

Test performed to detect pregnancy

Summary

Test performed to detect pregnancy

FieldValue
nameGravindex
purposepregnancy test
DiseasesDB
ICD10
MedlinePlus
eMedicine
OPS301
LOINC

Gravindex is an agglutination inhibition test performed on a urine sample to detect pregnancy. It is based on double antigen antibody reaction. The test detects the prevention of agglutination of HCG-coated latex particles by HCG present in the urine of pregnant women.

Procedure and results

Kits commercially available contain two reagents; one is a suspension of HCG-coated latex particles, and the other is a solution of HCG antibodies. One drop of the urine is mixed with one drop of antibody solution for one minute on a black glass slide. One drop of the HCG-coated latex particles is added to the slide and left for one minute.

  • If the level of HCG is too low, the antibodies will remain to agglutinate the HCG-coated latex particles. If agglutination occurs, the subject is not pregnant.
  • If the level of HCG is high, the HCG will bind to the antibodies, and thus no agglutination with the HCG-coated latex particles occurs. If no agglutination occurs, the subject is pregnant.

References

References

  1. (1974). "MCH Research Series". Health Services Administration, Bureau of Community Health Services..
  2. (2022-07-06). "Concise Textbook of Human Physiology - E-Book". Elsevier Health Sciences.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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