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Goblet cell carcinoid

Field	Value
name	Goblet cell carcinoid
synonyms	Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation
image	Goblet cell carcinoid -2- high mag.jpg
caption	Micrograph showing a goblet cell carcinoid. H&E stain.

The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.

Sign and symptoms

GCCs may present as appendicitis.

Diagnosis

GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).

Prognosis

GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.

Treatment

GCCs are treated with surgery.

References

(December 2007). "Goblet cell carcinoid of the appendix: a specific type of carcinoma". Histopathology.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

gastrointestinal-cancer

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