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Glycoside hydrolase family 9

Protein


Protein

FieldValue
SymbolGlyco_hydro_9
NameGlycosyl hydrolase family 9
PfamPF00759
Pfam_clanCL0059
PROSITEPDOC00511
SCOP1clc
CAZyGH9
Membranome family1017

In molecular biology, glycoside hydrolase family 9 is a family of glycoside hydrolases.

Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of 100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

Glycoside hydrolase family 9 CAZY GH_9 comprises enzymes with several known activities including endoglucanase () and cellobiohydrolase (). These enzymes were formerly known as cellulase family E. Cellulases (Endoglucanases) catalyse the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose. GH9 family members have also been found in green microalgae (Chlamydomonas, Gonium and Volvox) that show highest sequence identity to endogenous GH9 cellulases from invertebrate metazoans

References

References

  1. (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America.
  2. (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure.
  3. (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal.
  4. "Home".
  5. (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research.
  6. "Glycoside Hydrolase Family 9".
  7. (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology.
  8. Guerriero G. Sergeant K. Legay S. Hausman J.-F. Cauchie H.-M. Ahmad I. Siddiqui K.S . Int. J. Mol. Sci. 2018, 19, 1782
  9. "Prosite".
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