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Glycoside hydrolase family 53


FieldValue
SymbolGlyco_hydro_53
NameGlycosyl hydrolase family 53
imagePDB 1fob EBI.jpg
captioncrystal structure of beta-1,4-galactanase from aspergillus aculeatus at 100k
PfamPF07745
Pfam_clanCL0058
InterProIPR011683
SCOP1fob
OPM family117
OPM protein1hjq
CAZyGH53

In molecular biology, the glycoside hydrolase family 53 is a family of glycoside hydrolases , which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of 100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

These enzymes are endo-1,4- beta-galactanases . The structure of this domain is known and has a TIM barrel fold.

References

References

  1. (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America.
  2. (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure.
  3. (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal.
  4. "Home".
  5. (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research.
  6. "Glycoside Hydrolase Family 53".
  7. (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology.
  8. (December 2002). "Aspergillus aculeatus beta-1,4-galactanase: substrate recognition and relations to other glycoside hydrolases in clan GH-A". Biochemistry.
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