Surf Wiki
Save to docs
general/ec-3-2-1

From Surf Wiki (app.surf) — the open knowledge base

Glycoside hydrolase family 39

Family of glycoside hydrolases

Family of glycoside hydrolases

FieldValue
SymbolGlyco_hydro_39
NameGlycosyl hydrolases family 39
imagePDB 1uhv EBI.jpg
captioncrystal structure of beta-d-xylosidase from thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase
PfamPF01229
Pfam_clanCL0058
InterProIPR000514
PROSITEPDOC00787
SCOP1uhv
CAZyGH39

In molecular biology, glycoside hydrolase family 39 is a family of glycoside hydrolases.

Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of 100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

Glycoside hydrolase family 39 CAZY GH_39 comprises enzymes with several known activities; alpha-L-iduronidase (); beta-xylosidase ().

The most highly conserved regions in these enzymes are located in their N-terminal sections. These contain a glutamic acid residue which, on the basis of similarities with other families of glycosyl hydrolases, probably acts as the proton donor in their catalytic mechanism.

References

References

  1. (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America.
  2. (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure.
  3. (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal.
  4. "Home".
  5. (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research.
  6. "Glycoside Hydrolase Family 39".
  7. (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology.
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-3.2.1 glycoside-hydrolase-families protein-families
Want to explore this topic further?

Ask Mako anything about Glycoside hydrolase family 39 — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report