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Glomeruloid hemangioma

FieldValue
specialtyDermatology

Glomeruloid hemangioma is a distinctive vascular tumor first described in 1990 when found to be associated with POEMS syndrome and Castleman disease. Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules.

Signs and symptoms

Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules. They mostly reside on the trunk and proximal limbs and range in size from a few millimeters to a few centimeters in diameter. There have also been rare reports of glomeruloid hemangioma impacting the face. There have also been reports of eruptive angiomatous lesions, which resemble eruptive histiocytomas.

Causes

Glomeruloid hemangiomas are most commonly associated with POEMS syndrome, occurring in up to 45% of individuals with POEMS syndrome. Glomeruloid hemangiomas have also been associated with TAFRO syndrome. Rarely glomeruloid hemangiomas can occur in individuals with no systematic conditions.

Diagnosis

The histopathologic examination displays well-defined, dispersed dermal structures in different sizes that have resemblance to renal glomeruli. The central vessel is bigger and has a sinusoidal appearance, and it is surrounded by a network of small capillary vessels on the periphery.

References

References

  1. (2020). "Andrews' Diseases of the Skin: Clinical Dermatology". Elsevier.
  2. Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
  3. (2013). "Glomeruloid hemangioma in normal individuals". Medknow.
  4. (1985). "Cutaneous angiomas in POEMS syndrome". Elsevier BV.
  5. (2006). "Glomeruloid haemangioma with cerebriform morphology in a patient with POEMS syndrome". Oxford University Press (OUP).
  6. (2001). "Glomeruloid hemangioma –- a specific cutaneous marker of POEMS syndrome". Wiley.
  7. Perniciaro, Charles. (1995). "POEMS syndrome". Elsevier BV.
  8. Mocellin, Simone. (2021). "Soft Tissue Tumors". Springer International Publishing.
  9. (2018). "Glomeruloid hemangioma associated with TAFRO syndrome". Elsevier BV.
  10. (2022-01-29). "A Case of Oral Glomeruloid Hemangioma Without Systemic Conditions". Cureus.
  11. (2017). "Glomeruloid Hemangioma and POEMS Syndrome". Elsevier BV.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

dermal-and-subcutaneous-growths
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