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Giant solitary trichoepithelioma

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nameGiant solitary trichoepithelioma

Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter.

Signs and symptoms

Giant solitary trichoepithelioma primarily affects the perianal and groin region. They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.

Diagnosis

Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.

Treatment

The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.

References

References

  1. (2006). "Andrews' Diseases of the Skin: Clinical Dermatology". Saunders Elsevier.
  2. (2015). "Giant solitary trichoepithelioma". Georg Thieme Verlag KG.
  3. (2012). "A Giant Solitary Trichoepithelioma Originating from the Auricle". Dermatologic Surgery.
  4. (2017). "Giant solitary trichoepithelioma over the nose". Indian Journal of Dermatopathology and Diagnostic Dermatology.
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epidermal-nevi,-neoplasms,-and-cysts
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