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GelRed

DNA gel stain for molecular genetics


DNA gel stain for molecular genetics

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GelRed is an intercalating nucleic acid stain used in molecular genetics for agarose gel DNA electrophoresis. GelRed structurally consists of two ethidium subunits that are bridged by a linear oxygenated spacer.{{Citation | access-date = December 4, 2012

GelRed is a fluorophore, and its optical properties are essentially identical to those of ethidium bromide. When exposed to ultraviolet light, it fluoresces with an orange color that strongly intensifies after binding to DNA. The substance is marketed as a less toxic and more sensitive alternative to ethidium bromide. GelRed is sold as a solution in anhydrous DMSO or ultrapurified water. GelRed is unable to cross cell membranes.

References

References

  1. "GelRed and GelGreen: Environmentally safe and ultra-sensitive nucleic acid gel stains for replacing EtBr". Biotium Inc..
  2. (2012-01-01). "Molecular Biology Techniques". [[Academic Press]].
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