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Furanolactone

Furanolactone

The chemical structure of salvinorin A

A furanolactone is a heterocyclic chemical compound that contains both lactone and furan rings in its chemical structure.

Examples include:

  • The salvinorins, including the hallucinogenic compound salvinorin A
  • Columbin, a bitter diterpenoid from Calumbae Radix
  • Limonoids such as limonin, nomilin, and nomilinic acid
  • Tinosporide, a diterpenoid originally isolated from Tinospora cordifolia

References

References

  1. (2006). "Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring". Bioorg Med Chem Lett.
  2. (2002). "A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis". Cancer Lett.
  3. (1989). "Structure of columbin, a diterpenoid furanolactone from Tinospora cordifolia Miers". Acta Crystallogr C.
  4. (1989). "Structure of tinosporide, a diterpenoid furanolactone from Tinospora cordifolia Miers". Acta Crystallographica Section C.
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