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Fluid deprivation test

FieldValue
NameFluid/water deprivation test
Image[[File:Glass-half-full.jpegframelessupright=0.8]]
Caption
ICD10
ICD9
MeshID
OPS301
OtherCodes

Name = Fluid/water deprivation test | Image = [[File:Glass-half-full.jpeg|frameless|upright=0.8]]| Caption = | ICD10 = | ICD9 = | MeshID = | OPS301 = | OtherCodes = | A fluid or water deprivation test is a medical test which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia (a condition of excessive thirst that causes an excessive intake of water). The patient is required, for a prolonged period, to forgo intake of water completely, to determine the cause of the thirst.

This test measures changes in body weight, urine output, and urine composition when fluids are withheld. Sometimes measuring blood levels of ADH (a synonym for vasopressin) during this test is also necessary.

If there is no change in the water loss despite fluid deprivation, desmopressin may be administered to distinguish between the two types of diabetes insipidus which are central & nephrogenic diabetes insipidus.

The time of deprivation may vary from 4 to 18 hours.

The serum osmolality and urine osmolality are both measured in the test.

TOC

Interpretation of WDT

The conditions can be distinguished in the following way:

ConditionUrine osmolality in mOsm/kg, after fluid deprivationAfter desmopressin or vasopressin
Normal800800 (
a defect in ADH production (central/neurogenic diabetes insipidus)800 (50% increase)
a defect in the kidneys' response to ADH production (nephrogenic diabetes insipidus)
excessive intake of fluid (primary polydipsia)500500 (

References

References

  1. Choices, NHS. "Diabetes insipidus - Diagnosis - NHS Choices".
  2. Norman Lavin. (1 April 2009). "Manual of Endocrinology and Metabolism". Lippincott Williams & Wilkins.
  3. [http://www.gpnotebook.co.uk/simplepage.cfm?ID=-1435828200&linkID=28152 Water deprivation and desmopressin test at GPnote]
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

medical-tests thirst dynamic-endocrine-function-tests
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