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Flavoprotein pyridine nucleotide cytochrome reductases

A:229-424 A:229-424 A:985-1214 B:985-1214 A:274-493 A:274-493 A:274-493 A:274-493 B:261-481 A:261-481

Flavoprotein pyridine nucleotide cytochrome reductases catalyse the interchange of reducing equivalents between one-electron carriers and the two-electron-carrying nicotinamide dinucleotides. The enzymes include ferredoxin-NADP+ reductases, plant and fungal NAD(P)H:nitrate reductases, cytochrome b5 reductases, cytochrome P450 reductases, sulphite reductases, nitric oxide synthases, phthalate dioxygenase reductase, and various other flavoproteins.

Human proteins containing this domain

MTRR; NDOR1; NOS1; NOS2A; NOS3; NR1; POR;

References

References

  1. (1991). "The sequence of squash NADH:nitrate reductase and its relationship to the sequences of other flavoprotein oxidoreductases. A family of flavoprotein pyridine nucleotide cytochrome reductases". J. Biol. Chem..
  2. (1994). "Structure-function relations for ferredoxin reductase". J. Bioenerg. Biomembr..
  3. Siverio JM. (2002). "Assimilation of nitrate by yeasts". FEMS Microbiol. Rev..
  4. (1986). "Complete amino acid sequence of NADH-cytochrome b5 reductase purified from human erythrocytes". J. Biochem..
  5. Porter TD. (1991). "An unusual yet strongly conserved flavoprotein reductase in bacteria and mammals". Trends Biochem. Sci..
  6. (1989). "Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase". J. Biol. Chem..
  7. (1991). "Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase". Nature.
  8. (1993). "Structural prototypes for an extended family of flavoprotein reductases: comparison of phthalate dioxygenase reductase with ferredoxin reductase and ferredoxin". Protein Sci..
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