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Festuclavine dehydrogenase

Field	Value
Name	Festuclavine dehydrogenase
EC_number	1.5.1.44

Festuclavine dehydrogenase (, FgaFS, festuclavine synthase) is an enzyme with systematic name festuclavine:NAD+ oxidoreductase. This enzyme catalyses the following chemical reaction

: festuclavine + NAD+ \rightleftharpoons 6,8-dimethyl-6,7-didehydroergoline + NADH + H+

The enzyme takes part in the biosynthesis of fumigaclavine C.

References

(August 2010). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3". Organic & Biomolecular Chemistry.

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ec-1.5.1

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