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Eutylone

Designer drug of the cathinone class

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Eutylone (also known as β-keto-1,3-benzodioxolyl-N-ethylbutanamine, bk-EBDB, and N-ethylbutylone) is a stimulant and empathogenic drug of the phenethylamine, amphetamine, phenylisobutylamine, and cathinone families which was developed in the 1960s, which is classified as a designer drug. It was first reported to the EMCDDA in 2014 and became widespread internationally in 2019-2020 following bans on the related compound ephylone. It is a synthetic cathinone. In 2021, eutylone was the most common cathinone identified by the Drug Enforcement Administration in the United States.

Pharmacology

DAT	NET	SERT
120 ± 10	1280 ± 140	690 ± 50

Legal status

Sweden's public health agency suggested classifying eutylone as a hazardous substance, on September 25, 2019.

In the United States Eutylone is considered a schedule 1 controlled substance as a positional isomer of Pentylone.

References

Anvisa. (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial". [[Diário Oficial da União]].
"Substance Details Eutylone".
"Aryl-α-aminoketone derivatives".
(April 2021). "Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation". ACS Chemical Neuroscience.
(12 November 2023). "Eutylone". New Synthetic Drugs Database.
(August 2020). "Determining changes in new psychoactive substance use in Australia by wastewater analysis". The Science of the Total Environment.
(August 2020). "Eutylone Intoxications-An Emerging Synthetic Stimulant in Forensic Investigations". Journal of Analytical Toxicology.
(January 2021). "Analytically confirmed eutylone (bk-EBDB) exposure in emergency department patients". Clinical Toxicology.
(September 2022). "A fatal case of intoxication from a single use of eutylone: Clinical symptoms and quantitative analysis results". Leg Med (Tokyo).
(2021). "Emerging Threat Report".
(25 September 2019). "Tretton ämnen föreslås klassas som narkotika eller hälsofarlig vara". Folkhälsomyndigheten.
[https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf Lists of: Scheduling Actions. Controlled Substances. Regulated Chemicals]
(10 April 2023). "Federal Register :: Request Access".

Info: Wikipedia Source

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cathinones designer-drugs entactogens methylenedioxyphenethylamines phenylisobutylamines serotonin–norepinephrine–dopamine_reuptake_inhibitors

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