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Epithelial cell rests of Malassez

Part of the periodontal ligament cells around a tooth

Summary

Part of the periodontal ligament cells around a tooth

In dentistry, the epithelial cell rests of Malassez (ERM) or epithelial rests of Malassez (pax epithelialis pediodontii) are part of the periodontal ligament cells around a tooth. They are discrete clusters of residual cells from Hertwig's epithelial root sheath (HERS) that did not completely disappear. It is considered that these cell rests proliferate to form epithelial lining of various odontogenic cysts such as radicular cyst under the influence of various stimuli. They are named after Louis-Charles Malassez (1842–1909) who described them. Some rests become calcified in the periodontal ligament (cementicles).

ERM plays a role in cementum repair and regeneration. The stem cells in ERM can undergo an epithelial–mesenchymal transition and differentiate into diverse types of cells of mesodermal and ectodermal origin like bone, fat, cartilage and neuron-like cells.

References

References

  1. (August 2006). "The epithelial cell rests of Malassez – a role in periodontal regeneration?". Journal of Periodontal Research.
  2. (October 2013). "Role of the epithelial cell rests of M alassez in the development, maintenance and regeneration of periodontal ligament tissues". Periodontology 2000.
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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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