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Enterogastric reflex

Reflex inhibiting stomach emptying

Reflex inhibiting stomach emptying

The enterogastric reflex is one of the three extrinsic reflexes of the gastrointestinal tract, the other two being the gastroileal reflex and the gastrocolic reflex. TOC

Emptying inhibitory factors

The stomach's contents are inhibited from emptying into the small intestine by:

  • duodenal distension
  • duodenal acidic pH
  • duodenal hypertonicity
  • increased osmolarity of gastric chyme
  • sympathetic stimulation
  • intense pain
  • Cholecystokinin, Secretin, Vasoactive intestinal peptide
  • Nitric oxide, somatostatin from D cells

Emptying stimulatory factors

The stomach's contents empty through the pylorus, allowing digestion to proceed, when there is:

  • parasympathetic stimulation
  • increased volume and fluidity of gastric contents

References

References

  1. (22 July 2018). "Gastrointestinal Reflex Pathways".
  2. (April 1992). "Vagal and splanchnic sensory pathways mediate inhibition of gastric motility induced by duodenal distension". American Journal of Physiology. Gastrointestinal and Liver Physiology.
  3. "Enterogastric Reflex".
  4. (1969). "The slowing of gastric emptying by nine acids". The Journal of Physiology.
  5. "Factors That Regulate Gastric Emptying".
  6. (May 1975). "Control of gastric emptying by osmolality of duodenal contents in man". Gastroenterology.
  7. "Nervous System of the Digestive System - Gastrointestinal Reflex Pathways".
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