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Elliptocyte

Abnormal red blood cell

Elliptocyte
Summary

Abnormal red blood cell

FieldValue
nameCigar cells in elliptocytosis
imageElliptocytosis.jpg
captionBlood smear showing elliptocytes
fieldHematology
[[blood film]] in a patient with [[hereditary elliptocytosis]]: approximately 60% to 70% of the RBCs are '''elliptocytes'''.
Elliptocyte compared to other forms of [[poikilocytosis]].

Elliptocytes, also known as ovalocytes or cigar cells, are abnormally shaped red blood cells that appear oval or elongated, from slightly egg-shaped to rod or pencil forms. They have normal central pallor with the hemoglobin appearing concentrated at the ends of the elongated cells when viewed through a light microscope. The ends of the cells are blunt and not sharp like sickle cells.

Elliptocytes are commonly associated with hereditary elliptocytosis. However, they may also be seen in iron deficiency anemia, sepsis, malaria and other pathological states that decrease red blood cell turnover and or production. In the case of iron deficiency anemia, microcytosis and hypochromia would also be expected.

TOC

Causes

Rare elliptocytes (less than 1%) on a peripheral blood smear are a normal finding.

These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as:

  • Hereditary elliptocytosis and Southeast Asian ovalocytosis
  • Thalassemia
  • Iron deficiency
  • Myelodysplastic syndrome and myelofibrosis
  • Megaloblastic anemia

References

References

  1. "Ovalocytes/Elliptocytes - LabCE.com, Laboratory Continuing Education".
  2. (2003). "Clinical hematology and oncology : presentation, diagnosis, and treatment". Churchill Livingstone.
  3. (2021). "Robbins & Cotran pathologic basis of disease".
  4. (2007). "Wintrobe's atlas of clinical hematology". Lippincott Williams & Wilkins.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

blood-cells human-cells hematology blood-disorders blood-tests
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