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Elephantiasis nostras

Field	Value
image	The other image of the rare disease elphantasis nostras v errucosa.jpg
specialty	dermatology

Elephantiasis nostras, also known as "Holliman's Edema," is a disease that usually affects the lower legs or scrotum. Swelling is accompanied by rough nodules or wart-like plaques on the skin. If the disease is not treated, it eventually results in pain and immobility.

The disease can be described as a cutaneous condition, a final hypertrophic fibrosis following long standing chronic lymphangitis.

Causes

Although elephantiasis nostras resembles the elephantiasis caused by helminths, it is not a filarial disease. Instead, it is a complication of chronic lymphedema. Both elephantiasis nostras and filarial elephantiasis are characterized by impaired lymphatic drainage, which results in excess fluid accumulation.

Treatment

Treatment consists of antibiotics, elevation of the affected limb, and compression. For persons with elephantiasis nostras who are overweight or obese, weight loss is recommended. Oral retinoids have been used to treat the cutaneous manifestations of the disease.

References

Lin P, Phillips T. "Vascular Disorders: Ulcers" (2003). In Bolognia JL, Jorizzo JL, Rapini RP (Eds.), ''Dermatology'', p. 1637. Mosby {{ISBN. 0-323-02409-2
Scheinfeld NS. (2009). "[http://www.consultantlive.com/display/article/10162/1427239 Skin Disorders in Older Adults: Vascular, Lymphatic, and Purpuric Dermatitides, Part 2] {{Webarchive. link. (2012-09-24 ". ''Consultant'' 49 ('''7'''))
(2006). "Andrews' Diseases of the Skin: clinical Dermatology". Saunders Elsevier.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

bacterium-related-cutaneous-conditions

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