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Elephantiasis

Enlargement and hardening of body parts due to swelling

Enlargement and hardening of body parts due to swelling

FieldValue
nameElephantiasis
imageGould Pyle 275.jpg
captionElephantiasis of the legs due to filariasis.
fieldInfectious disease, general surgery
symptomsSwelling of the skin

Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling (edema). It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels (lymphedema). It may affect the genitalia. The term elephantiasis is often used in reference to symptoms caused by parasitic worm infections, but may refer to a variety of diseases that swell parts of the subject's body to exceptionally massive proportions. TOC

Cause

Some conditions that present with elephantiasis include the following:

  • Elephantiasis nostras, due to longstanding chronic lymphangitis.
  • Elephantiasis tropica (known as lymphatic filariasis), caused by a number of parasitic worms, particularly Wuchereria bancrofti. More than 120 million people, mostly in Africa and Southeast Asia, are affected.
  • Nonfilarial elephantiasis (or podoconiosis), an immune disease affecting the lymph vessels
  • Leishmaniasis
  • Elephantiasis, Grade 3 lymphedema, which may occur in people with breast cancer
  • Genital elephantiasis, result of lymphogranuloma venereum
  • Proteus syndrome, a genetic disorder best known as the condition possibly experienced by Joseph Merrick, the so-called Elephant Man

Other causes may include the following:

  • Repeated streptococcal infection
  • Lymphadenectomy
  • Hereditary birth defects
  • Pretibial myxedema

Other diseases, such as the rare Klippel–Trénaunay syndrome, can initially be misdiagnosed as elephantiasis.

Elephantiasis may have been the skin condition suffered by Biblical character Job.

References

References

  1. "Definition of ELEPHANTIASIS".
  2. "elephantiasis". The Free Dictionary.
  3. (27 March 2013). "Taking the 'Bite' Out of Vector-Borne Diseases - Inside Life Science Series - National Institute of General Medical Sciences". publications.nigms.nih.gov.
  4. (29 May 2015). "Lymphedema". National Cancer Institute.
  5. https://www.biblicalcyclopedia.com/J/jobs-disease.html
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

symptoms-and-signs:-skin-and-subcutaneous-tissue diseases-of-veins,-lymphatic-vessels-and-lymph-nodes
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