Surf Wiki
Save to docs
general/ec-2-5-1

From Surf Wiki (app.surf) — the open knowledge base

Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)

FieldValue
NameDitrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)
EC_number2.5.1.87

Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) (, RER2, Rer2p, Rer2p Z-prenyltransferase, Srt1p, Srt2p Z-prenyltransferase, ACPT, dehydrodolichyl diphosphate synthase 1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10--55 isopentenyl units). This enzyme catalyses the following chemical reaction

: (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate \rightleftharpoons n diphosphate + ditrans, polycis-polyprenyl diphosphate (n \rightleftharpoons 10--55)

The enzyme is involved in biosynthesis of dolichol (a long-chain polyprenol) with a saturated alpha-isoprene unit.

References

References

  1. (June 2001). "Yeast Saccharomyces cerevisiae has two cis-prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis". Genes to Cells.
  2. (June 2007). "Precise bacterial polyprenol length control fails in Saccharomyces cerevisiae". Biopolymers.
  3. (January 1999). "The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis". Molecular and Cellular Biology.
  4. (June 2000). "Molecular cloning, expression, and functional analysis of a cis-prenyltransferase from Arabidopsis thaliana. Implications in rubber biosynthesis". The Journal of Biological Chemistry.
  5. (July 2000). "Characterization of dehydrodolichyl diphosphate synthase of Arabidopsis thaliana, a key enzyme in dolichol biosynthesis". FEBS Letters.
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-2.5.1
Want to explore this topic further?

Ask Mako anything about Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report