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Dipeptidyl-peptidase IV family


FieldValue
SymbolDPPIV_N
NameDipeptidyl peptidase IV (DPP IV) N-terminal region
imagePDB 2ajc EBI.jpg
captionporcine dipeptidyl peptidase iv (cd26) in complex with 4-(2-aminoethyl)-benzene sulphonyl fluoride (aebsf)
PfamPF00930
Pfam_clanCL0186
InterProIPR002469
PROSITEPDOC00587
MEROPSS9
SCOP1n1m
Membranome superfamily321

In molecular biology, the dipeptidyl-peptidase IV family is a family of serine peptidases which belong to MEROPS peptidase family S9 (clan SC), subfamily S9B (dipeptidyl-peptidase IV). The protein fold of the peptidase domain for members of this family resembles that of serine carboxypeptidase D, the type example of clan SC. The type example of this family is Dipeptidyl peptidase-4.

Human proteins in this family are:

  • Dipeptidyl peptidase-4
  • Dipeptidyl peptidase 8
  • Dipeptidyl peptidase 9
  • Inactive dipeptidyl peptidase 10
  • Dipeptidyl aminopeptidase-like protein 6
  • Seprase

References

References

  1. (July 1992). "Molecular cloning and sequence analysis of human dipeptidyl peptidase IV, a serine proteinase on the cell surface". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression.
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