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Dimethyldiethoxysilane
| author-link = | publication-date = | publication-place = Boca Raton, FL | NFPA-H = | NFPA-F = | NFPA-R = Dimethyldiethoxysilane, sometimes abbreviated DMDEOS or DMDES, is an organosilicon compound. DMDEOS is a precursor in the production of the silicone polymer polydimethylsiloxane (PDMS).
DMDEOS is an intermediate silane useful for blocking hydroxyl and amino groups in organic synthesis reactions. This silylating step allows subsequent reactions to be carried out which would be adversely affected by the presence of active hydrogen in the hydroxyl or amine groups. Following the reaction step, hydroxyl or amine groups blocked with DMDEOS may be recovered by a hydrolysis procedure. DMDEOS is also used for preparing hydrophobic and release materials as well as enhancing flow of powders.
| author-link = | publication-date = | publication-place =
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