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DHH phosphatase family

Field	Value
Symbol	DHH
Name	DHH family
image	PDB 1i74 EBI.jpg
caption	streptococcus mutans inorganic pyrophosphatase
Pfam	PF01368
InterPro	IPR001667
SCOP	1i74

In molecular biology, the DHH phosphatase family is a family of putative phosphoesterases. The family includes Drosophila prune protein and bacterial RecJ exonuclease. The RecJ protein of Escherichia coli plays an important role in a number of DNA repair and recombination pathways. RecJ catalyses processive degradation of single-stranded DNA in a 5'-to-3' direction. Sequences highly related to those encoding RecJ can be found in many of the eubacterial genomes sequenced to date.

References

(January 1998). "A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease". Trends in Biochemical Sciences.
(February 2000). "A thermostable single-strand DNase from Methanococcus jannaschii related to the RecJ recombination and repair exonuclease from Escherichia coli". Journal of Bacteriology.

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