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D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase


FieldValue
NameD-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
EC_number2.7.7.70

D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase (, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-glycero-D-manno-heptose-1beta-phosphate adenylyltransferase, hldE (gene), rfaE (gene)) is an enzyme with systematic name ATP:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase. This enzyme catalyses the following chemical reaction

: D-glycero-beta-D-manno-heptose 1-phosphate + ATP \rightleftharpoons ADP-D-glycero-beta-D-manno-heptose + diphosphate

The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose.

References

References

  1. (January 2000). "The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose". Journal of Bacteriology.
  2. (January 2002). "Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli". Journal of Bacteriology.
  3. (July 2002). "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology.
  4. (February 2010). "Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB)". Biochemistry.
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