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Connective tissue nevus

Field	Value
name	Connective tissue nevus
image	SkinTumors-PA100988.jpg
synonyms	Collagenoma, Elastoma, and Shagreen patch
caption	Storiform collagenoma, H&E stain
field	Dermatology

| A connective tissue nevus is a skin lesion which may be present at birth or appear within the first few years of life. It is elevated, soft to firm in consistency, varying in size from 0.5 to several centimeters in diameter, and may manifest as grouped, linear, or irregularly-distributed lesions.

Signs and symptoms

Connective tissue nevi are thickened regions of skin that look as a series of skin-colored papules and plaques. The spots will become discolored in a yellowish manner as the skin covering them is stretched. Occasionally, they could seem red and have enhanced vascularity.

Causes

The majority of reports are of random lesions, but there are some familial cases, indicating autosomal dominant transmission. Furthermore, connective tissue nevus can present as solitary lesions or be a component of systemic illnesses like tuberous sclerosis, which features shagreen's patches, another form of collagenoma, as an associated feature, or Buschke–Ollendorff syndrome, which is linked to collagenomas and elastomas.

Diagnosis

In addition to hematoxylin-eosin staining to evaluate histological changes, lesion characteristics, genetic history, and special histochemical staining to highlight the composition of connective tissue nevus for differentiation, these tests are necessary for the diagnosis of connective tissue nevus.

References

Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. {{ISBN. 0-07-138076-0.
Weston, William L.. (2007). "Color Textbook of Pediatric Dermatology". Elsevier.
Saussine, Anne. (2012). "Connective tissue nevi: An entity revisited". Elsevier BV.
McCuaig, Catherine C.. (2012). "Connective tissue nevi in children: Institutional experience and review". Elsevier BV.
Pope, V.. (2016-03-08). "Buschke–Ollendorff syndrome: a novel case series and systematic review". Oxford University Press (OUP).
Arora, Harleen. (2017). "Connective Tissue Nevi: A Review of the Literature". Ovid Technologies (Wolters Kluwer Health).
Yang, Qingqing. (2022-10-25). "Connective tissue nevus—Isolated collagenoma". Wiley.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

dermal-and-subcutaneous-growths

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