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Collecting duct carcinoma

Type of kidney cancer

Field	Value
name	Collecting duct carcinoma
synonyms	Bellini duct carcinoma
image	Collecting duct carcinoma - 2 WBAL.tif
caption	Collecting duct carcinoma. H&E stain.
field	oncology/nephrology

Collecting duct carcinoma in computed tomography

Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers. It is also recently described; a 2002 review found just 40 case reports worldwide. Previously, due to its location, CDC was commonly diagnosed as renal cell carcinoma or a subtype of renal cell carcinoma. However, CDC does not respond well to chemotherapy drugs used for renal cell carcinoma, and progresses and spreads more quickly.

Signs and symptoms

Signs and symptoms are as for kidney cancer.

Histology

Histologic examination of collecting duct carcinoma demonstrates an infiltrative lesion with tubulopapillary, irregular channels lined by high grade hobnail cells with marked desmoplastic response and brisk neutrophilic infiltrate.

History

CDC was thought to be renal cell carcinoma, until "recently developed techniques of lectin histochemistry" helped forward knowledge of kidney duct cancers.

References

"Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma". Am. J. Surg. Pathol.. (March 2009)
"Major response and clinical benefit following third-line treatment for Bellini duct carcinoma". Wien. Klin. Wochenschr.. (January 2005)
"Bellini duct carcinoma: review of diagnosis and management". Int Urol Nephrol. (2002). link
"Is there a place for radical nephrectomy in the presence of metastatic collecting duct (Bellini) carcinoma?". J. Urol.. (April 2003)
O Natsume. (1997). "Bellini duct carcinoma: a case report". Japanese Journal of Clinical Oncology.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

rare-cancers kidney-cancer

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