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Cochlear duct

Cavity in the cochlea of the inner ear

Field	Value
Name	Cochlear duct
Latin	ductus cochlearis
Image	Blausen 0329 EarAnatomy InternalEar.png
Caption	Inner ear, with cochlear duct labeled near bottom.
Width	400px
Image2	Gray928.png
Caption2	Diagrammatic longitudinal section of the cochlea. (visible at far right under latin name ductus cochlearis)
System	Ear

The cochlear duct (a.k.a. the scala media) is an endolymph filled cavity inside the cochlea, located between the tympanic duct and the vestibular duct, separated by the basilar membrane and the vestibular membrane (Reissner's membrane) respectively. The cochlear duct houses the organ of Corti.

Structure

The cochlear duct is part of the cochlea. It is separated from the tympanic duct (scala tympani) by the basilar membrane. It is separated from the vestibular duct (scala vestibuli) by the vestibular membrane (Reissner's membrane). The stria vascularis is located in the wall of the cochlear duct.

Development

The cochlear duct develops from the ventral otic vesicle (otocyst). It grows slightly flattened between the middle and outside of the body. This development may be regulated by the genes EYA1, SIX1, GATA3, and TBX1. The organ of Corti develops inside the cochlear duct.

Function

The cochlear duct contains the organ of Corti. This is attached to the basilar membrane. It also contains endolymph, which contains high concentrations of K+ for the function of inner hair cells and outer hair cells in the organ of Corti.

Clinical significance

Drugs delivered directly to the tympanic duct will spread to all of the cochlea except for the cochlear duct. Rarely, the cochlear duct may develop to have the wrong shape.

Additional images

File:Gray903.png|Transverse section of the cochlear duct of a fetal cat. File:Gray924.png|The membranous labyrinth. File:Gray929.png|Floor of ductus cochlearis. File:Cochlea-crosssection.svg|Cross section of the cochlea.

References

(2013). "Handbook of Clinical Neurophysiology". [[Elsevier]].
Feher, Joseph. (2012). "Quantitative Human Physiology – An Introduction". [[Academic Press]].
Fekete, D. M.. (2009). "Encyclopedia of Neuroscience". [[Academic Press]].
(2018). "Current Topics in Developmental Biology". [[Elsevier]].
Spelman, Francis A.. (2013). "Biomaterials Science – An Introduction to Materials in Medicine". [[Academic Press]].
(2015). "Implantable Neuroprostheses for Restoring Function". [[Woodhead Publishing]].

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ear auditory-system inner-ear otorhinolaryngology hearing otology human-head-and-neck

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