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Cefsulodin

Chemical compound

Summary

Chemical compound

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Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977.

TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985.

Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms. This agar is most often used in water and beverage testing.

Susceptibility data

The following represents MIC susceptibility data for various P. aeruginosa strains:

  • Pseudomonas aeruginosa PA13 (resistant strain): 32 μg/ml
  • Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml

References

References

  1. "TOKU-E Technical Application Sheet".
  2. (1984). "Cefsulodin and ceftazidime, two antipseudomonal cephalosporins". Clinical Pharmacy.
  3. (1984). "Activity of cefsulodin and other agents against Pseudomonas aeruginosa". Reviews of Infectious Diseases.
  4. (November 1986). "Cefsulodin". Drug Intelligence & Clinical Pharmacy.
  5. (15 April 1985). "Lupron Is First Abbott-Takeda Product to Reach U.S. Market". Pink Sheet.
  6. "BAM Media M35: Cefsulodin-Irgasan Novobiocin Agar or Yersinia Selective Agar".
  7. "Cefsulodin | the Antimicrobial Index Knowledgebase - TOKU-E".
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

cephalosporin-antibiotics isonicotinamides drugs-developed-by-takeda-pharmaceutical-company sulfonates
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