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CD78

Protein found in humans

CD78 is a protein expressed on the surface of some immature and all mature B-cells. It is considered a pan-B cell antigen.{{cite journal |access-date=2008-10-28

Function

It is part of the MHC class II.

Expression

CD78 is expressed on all stages of B cell development from pre-B cell through plasma cells.{{cite book

It is also present on tissue macrophages and on epithelial cells.

Clinical significance

With flow cytometry, it can be used to detect B cells during many stages of their development. It is one of relatively few markers usefully expressed on plasma cells, and when combined with detection of markers such as CD22, can be used to determine the relative proportion of plasma cells.

References

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

clusters-of-differentiation

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