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CAZy

Enzyme database

Summary

Enzyme database

Field	Value
title	CAZy
logo	[[File:Database.png]]
description	carbohydrate-active enzymes database
center	AFMB, French National Centre for Scientific Research
laboratory	Glycogenomics group
citation	Lombard & al. (2014)
url	http://www.cazy.org/
webapp	http://research.ahv.dk/cazy

the database

http://mothra.ornl.gov/cgi-bin/cat/cat.cgi http://csbl.bmb.uga.edu/dbCAN/ CAZy is a database of Carbohydrate-Active enZYmes (CAZymes). The database contains a classification and associated information about enzymes involved in the synthesis, metabolism, and recognition of complex carbohydrates, i.e. disaccharides, oligosaccharides, polysaccharides, and glycoconjugates. Included in the database are families of glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and non-catalytic carbohydrate-binding modules. The CAZy database also includes a classification of Auxiliary Activity redox enzymes involved in the breakdown of lignocellulose.

CAZy was established in 1999 in order to provide online and constantly updated access to the protein sequence-based family classification of CAZymes, which was originally developed in early 1990s to classify the glycoside hydrolases. CAZy continues to be curated and developed by the Glycogenomics group at AFMB, a research centre affiliated with the French National Centre for Scientific Research and Aix-Marseille University.

The CAZy database is coupled with CAZypedia, which was launched in 2007 as a research community-driven, wiki-based encyclopedia of CAZymes.

Classification

CAZy identifies evolutionarily related families of glycosyl hydrolases using the classification introduced by Bernard Henrissat.{{Cite journal

References

(January 2009). "The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics". Nucleic Acids Res..
(2017). "Structural diversity of carbohydrate esterases". Biotechnology Research and Innovation.
(2017). "Advances in molecular engineering of carbohydrate-binding modules". Proteins.
(March 2013). "Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes". Biotechnol Biofuels.
(2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research.
link. (2014-08-10 , [http://www.cazy.org/GlycosylTransferases.html Glycosyltransferase], [http://www.cazy.org/Polysaccharide-Lyases.html Polysaccharide Lyase], [http://www.cazy.org/Carbohydrate-Esterases.html Carbohydrate Esterase], [http://www.cazy.org/Auxiliary-Activities.html Auxiliary-Activity] {{Webarchive). link. (2013-10-30 , and [http://www.cazy.org/Carbohydrate-Binding-Modules.html Carbohydrate-Binding Module] section page.)
"About".
"AFMB UMR 7257 - UMR7257 : CNRS - AIX MARSEILLE UNIV".
(2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology.
(2008). "Sorting the diverse: The sequence‑based classifications of carbohydrate‑active enzymes". The Biochemist.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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