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Carboxypeptidase U

Field	Value
Name	Carboxypeptidase U
EC_number	3.4.17.20
CAS_number	156621-18-0

Carboxypeptidase U (, arginine carboxypeptidase, carboxypeptidase R, plasma carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor) is an enzyme. This enzyme catalyses the following chemical reaction

: Release of C-terminal Arg and Lys from a polypeptide

Pro-carboxypeptidase U in (human) plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U.

References

(November 1991). "Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma". The Journal of Biological Chemistry.
(1994). "Pro-carboxypeptidase R cleaves bradykinin following activation". International Archives of Allergy and Immunology.
(June 1994). "Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen". The Journal of Biological Chemistry.
(May 1995). "Activation and characterization of procarboxypeptidase B from human plasma". Biochemistry.
(November 1996). "Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma". Blood.

Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-3.4.17

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