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Carboxynorspermidine synthase

FieldValue
NameCarboxynorspermidine synthase
EC_number1.5.1.43

Carboxynorspermidine synthase (, carboxynorspermidine dehydrogenase, carboxyspermidine dehydrogenase, CASDH, CANSDH) is an enzyme with systematic name carboxynorspermidine:NADP+ oxidoreductase. This enzyme catalyses the following chemical reactions

: (1) carboxynorspermidine + H2O + NADP+ \rightleftharpoons L-aspartate 4-semialdehyde + propane-1,3-diamine + NADPH + H+ : (2) carboxyspermidine + H2O + NADP+ \rightleftharpoons L-aspartate 4-semialdehyde + putrescine + NADPH + H+

The reaction takes place in the opposite direction.

References

References

  1. (July 1991). "Purification and some properties of carboxynorspermidine synthase participating in a novel biosynthetic pathway for norspermidine in Vibrio alginolyticus". Journal of General Microbiology.
  2. (April 2009). "An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae". The Journal of Biological Chemistry.
  3. (December 2011). "Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota". The Journal of Biological Chemistry.
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ec-1.5.1
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