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Brodmann area 9

Part of the frontal cortex in the brain of humans and other primates


Summary

Part of the frontal cortex in the brain of humans and other primates

FieldValue
NameBrodmann area 9
Latinarea frontalis granularis
ImageBrodmann area 9.png
Width250
Image2Brodmann Cytoarchitectonics 9.png

Brodmann area 9, or BA9, refers to a cytoarchitecturally defined portion of the frontal cortex in the brain of humans and other primates. Its cytoarchitecture is referred to as granular due to the concentration of granule cells in layer IV. It contributes to the dorsolateral and medial prefrontal cortex.

Functions

Research has identified the area as being variously involved in short term memory, verbal fluency, error detection, auditory verbal attention, and inductive reasoning; functions also include evaluating recency, overriding automatic responses, inferring the intention of others, inferring deduction from spatial imagery, and attributing intention. In one investigation, the area saw engagement while study participants counted a series of auditory stimuli. The area displays lower levels of energy consumption in individuals suffering from bipolar disorder.

The area found on the left hemisphere is at least partially responsible for working memory, empathy, idiom comprehension, and self-criticism. Additional capabilities encompass processing pleasant and unpleasant emotional scenes, and attending to negative emotions.

On the right hemisphere, the region is involved in the attribution of intention, theory of mind, working memory, and spatial memory. Recognition and recall are also capabilities, while further functions in this area encompass planning, calculation, religiosity, semantic and perceptual processing of odors, recognition of others' emotions, and attention to positive emotions.

Guenon

Brodmann area 9 also exists in the frontal lobe of the guenon. Brodmann-1909 regarded it on the whole as topographically and cytoarchitecturally homologous to the granular frontal area 9 and frontopolar area 10 in the human. Distinctive features (Brodmann-1905): Unlike Brodmann area 6 (Brodmann-1909), area 9 has a distinct internal granular layer (IV); unlike Brodmann area 6 or Brodmann area 8 (Brodmann-1909), its internal pyramidal layer (V) is divisible into two sublayers, an outer layer 5a of densely distributed medium-size ganglion cells that partially merges with layer IV, and an inner, clearer, cell-poor layer 5b; the pyramidal cells of sublayer 3b of the external pyramidal layer (III) are smaller and sparser in distribution; the external granular layer (II) is narrow, with small numbers of sparsely distributed granule cells.

Image

File:Brodmann area 9 animation small.gif|Animation. File:Brodmann area 9 frontal.jpg|front view. File:Brodmann area 9 lateral.jpg|Lateral view. File:Brodmann area 9 medial.jpg|Medial view.

References

References

  1. Vasković, Jana. (2023-11-03). "Cytoarchitecture of cerebral cortex". Kenhub GmbH.
  2. (May 2005). "Human cortical responses during one-bit delayed-response tasks: an fMRI study". Brain Research Bulletin.
  3. (September 2003). "Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses". Human Brain Mapping.
  4. (December 2007). "Dissociation of response inhibition and performance monitoring in the stop signal task using event-related fMRI". Human Brain Mapping.
  5. (2005). "An FMRI study to investigate auditory attention: a model of the cocktail party phenomenon". Magnetic Resonance in Medical Sciences.
  6. (March 1997). "The seats of reason? An imaging study of deductive and inductive reasoning". NeuroReport.
  7. (November 1996). "Activation of the prefrontal cortex during judgments of recency: a functional MRI study". NeuroReport.
  8. (August 2006). "Automaticity and reestablishment of executive control-an fMRI study". Journal of Cognitive Neuroscience.
  9. (September 1995). "Modeling other minds". NeuroReport.
  10. (April 2002). "Spatial imagery in deductive reasoning: a functional MRI study". Brain Research. Cognitive Brain Research.
  11. (March 1999). "The neural consequences of conflict between intention and the senses". Brain.
  12. (2008). "The multiple dimensions of sustained attention". Cortex.
  13. (December 2010). "Prefrontal and paralimbic metabolic dysregulation related to sustained attention in euthymic older adults with bipolar disorder". Bipolar Disorders.
  14. (Sep 2012). "Gamma-band activity in human prefrontal cortex codes for the number of relevant items maintained in working memory". J. Neurosci..
  15. (August 2001). "Investigating the functional anatomy of empathy and forgiveness". NeuroReport.
  16. (August 1997). "Activation of left posterior cingulate gyrus by the auditory presentation of threat-related words: an fMRI study". Psychiatry Research.
  17. (January 2008). "Idiom comprehension: a prefrontal task?". Cerebral Cortex.
  18. (January 2010). "Having a word with yourself: neural correlates of self-criticism and self-reassurance". NeuroImage.
  19. (November 1997). "Neuroanatomical correlates of pleasant and unpleasant emotion". Neuropsychologia.
  20. (January 2012). "Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters". Psychological Medicine.
  21. (February 2000). "A PET investigation of the attribution of intentions with a nonverbal task". NeuroImage.
  22. (July 2002). "Imaging the intentional stance in a competitive game". NeuroImage.
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  25. (February 2002). "Neuroimaging a single thought: dorsolateral PFC activity associated with refreshing just-activated information". NeuroImage.
  26. (2006). "Prefrontal cortex hemispheric specialization for categorical and coordinate visual spatial memory". Neuropsychologia.
  27. (May 2002). "Sustained mnemonic response in the human middle frontal gyrus during on-line storage of spatial memoranda". Journal of Cognitive Neuroscience.
  28. (2003). "Prefrontal activity associated with working memory and episodic long-term memory". Neuropsychologia.
  29. (December 1996). "Differential activation of the prefrontal cortex in successful and unsuccessful memory retrieval". Brain.
  30. (1999). "Positron emission tomography correlations in and beyond medial temporal lobes". Hippocampus.
  31. (March 1994). "Neuroanatomical correlates of retrieval in episodic memory: auditory sentence recognition". Proceedings of the National Academy of Sciences of the United States of America.
  32. (June 2001). "Comparative electrophysiological and hemodynamic measures of neural activation during memory-retrieval". Human Brain Mapping.
  33. (March 2002). "Neural mechanisms of planning: a computational analysis using event-related fMRI". Proceedings of the National Academy of Sciences of the United States of America.
  34. (June 2003). "The fMRI study of the calculation tasks in normal aged volunteers". Journal of Peking University.
  35. (2000). "The calculating brain: an fMRI study". Neuropsychologia.
  36. (April 2001). "Neural correlates of religious experience". The European Journal of Neuroscience.
  37. (January 1999). "Functional anatomy of perceptual and semantic processing for odors". Journal of Cognitive Neuroscience.
  38. (August 2006). "Attentional modulation of emotional stimulus processing: an fMRI study using emotional expectancy". Human Brain Mapping.
  39. (November 2014}} {{cite web). ["BrainInfo"](http://braininfo.rprc.washington.edu/centraldirectory.aspx?type=a&ID=1046}}{{unreliable source?).
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