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Bladder sphincter dyssynergia

Field	Value
name	Bladder sphincter dyssynergia
synonyms	Detrusor sphincter dyssynergia
image	Bladder Sphincter Dyssynergia Urodynamic Trace.jpg
caption	Urodynamic trace of detrusor sphincter dyssynergia

Bladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury or multiple sclerosis which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the detrusor muscles of the bladder and the male or female external urethral sphincter muscles. In normal lower urinary tract function, these two separate muscle structures act in synergistic coordination. But in this neurogenic disorder, the urethral sphincter muscle, instead of relaxing completely during voiding, dyssynergically contracts causing the flow to be interrupted and the bladder pressure to rise.

Treatment

Botulinum A toxin is a valuable alternative for patients who do not want surgical methods.

References

(1999). "The standardization of terminology in neurogenic lower urinary tract dysfunction: with suggestions for diagnostic procedures. International Continence Society Standardization Committee". Neurourology and Urodynamics.
(October 2005). "Understanding detrusor sphincter dyssynergia--significance of chronology". Urology.
(2004). "[Tamsulosin in the treatment of detrusor-sphincter dyssynergia of the urinary bladder in patients with multiple sclerosis]". Urologiia.
(2004). "Textbook of the neurogenic bladder: adults and children". Informa Health Care.
(October 1997). "Botulinum A toxin as a treatment of detrusor-sphincter dyssynergia in patients with spinal cord injury: MRI controlled transperineal injections". Journal of Neurology, Neurosurgery, and Psychiatry.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

urinary-bladder-disorders

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