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Bamipine

Chemical compound

Summary

Chemical compound

| Drugs.com =

Bamipine (trade name Soventol) is a pharmaceutical drug acting as an H1 antihistamine with anticholinergic properties. It is used as an antipruritic ointment. No oral use is known.

Adverse effects

Side effects are typical of an old (first-generation) antihistamine: tiredness in adults, agitation in children, mydriasis (dilation of the pupils). These effects are rare when bamipine is applied topically as an ointment. Allergic and hypersensitivity reactions are also rare. Acute eczema can be worsened by bamipine ointment.

Contraindications and interactions

No clinically relevant contraindications or interactions with other drugs are known.

Pharmacology

Pharmacokinetics

When applied topically, the maximal effect is reached after 20 to 60 minutes and lasts up to 48 hours. Bamipine is not absorbed through intact skin in relevant doses.

References

References

  1. Publishing, William Andrew. (2013-10-22). "Pharmaceutical Manufacturing Encyclopedia, 3rd Edition". Elsevier.
  2. (2017). "Piperidine-based drug discovery".
  3. "Pharmaceutical compositions containing tiotropium salts and antihistamines and their use".
  4. {{drugs.com. international. bamipine: Bamipine.
  5. (2015). "Austria-Codex". Österreichischer Apothekerverlag.
Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

piperidines h1-receptor-antagonists
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