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Baboon syndrome

Field	Value
image	Baboon syndrome hariadhi.svg
specialty	dermatology

Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), popularly known as baboon syndrome because of its resemblance to the distinctive red buttocks displayed by female baboons, is a systemic dermatitis characterized by well-demarcated patches of erythema distributed symmetrically on the buttocks. The cause of the syndrome may be drug-related: i.e., induced by systemic administration of hydroxyzine, penicillin, iodinated radio contrast media, and others.

Symptoms and signs

The typical rash commonly appears on buttocks. This then resembles the colour of a baboon's buttocks. Other areas like upper inner thigh and armpits, may be affected by the rash. The rashes are red and well-defined. The presentation is typically symmetrical and not associated with systemic symptoms.

Diagnosis

Treatment

Treatment of symmetrical drug related intertriginous and flexural exanthema involves identifying and stopping the causative agent. Topical steroids can help to reduce the redness.

Epidemiology

Baboon syndrome affects both sexes equally, and can occur at any age, but seems to be more common in childhood than in adulthood.

References

(2007). "Dermatology: 2-Volume Set". Mosby.
(May 2013). "Baboon syndrome induced by hydroxyzine". Indian Journal of Dermatology.
(April 2009). "SDRIFE (baboon syndrome) induced by penicillin". Clinical and Experimental Dermatology.
(2007). "Recurrent flexural exanthema (SDRIFE or baboon syndrome) after administration of two different iodinated radio contrast media". Dermatology.
(2009). "Baboon syndrome and segmental vitiligo coexistence". The Turkish Journal of Pediatrics.
"Symmetrical drug related intertriginous and flexural exanthema". DermNet NZ.
(2004). "Baboon syndrome in childhood: easy to avoid, easy to diagnose, but the problem continues". Pediatric Dermatology.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

contact-dermatitis syndromes-affecting-the-skin

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