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Auspitz's sign

Dermatologic sign

Dermatologic sign

Auspitz's sign is the appearance of punctate bleeding spots when psoriasis scales are scraped off, named after Heinrich Auspitz. It may also be seen in Darier's disease and actinic keratosis.

Importantly, as with many eponymous clinical signs, Heinrich Auspitz was not the first to discover the sign named after him. It was Auspitz's mentor at the Medical University of Vienna (Ferdinand von Hebra) and Parisian dermatologist Marie Devergie who first noted the punctate hemorrhages underlying psoriasis scales.

This pinpoint bleeding results from a thinning of the epidermal layer overlying the tips of the dermal papillae. Blood vessels within the papillae are dilated and tortuous, and often bleed readily when the scale is removed.

Although classically associated with psoriasis, subsequent research has found Auspitz's sign to be of very little diagnostic value for the disease. This is because several other diseases display the sign (including Darier's disease and actinic keratosis). Additionally, only a minority of psoriasis scales show it when removed (

References

References

  1. {{WhoNamedIt. synd. 101. Auspitz' symptom
  2. (July 2006). "Dermatologic Signs". Journal of Cutaneous Medicine and Surgery.
  3. (1 September 2007). "Head to Head: Should eponyms be abandoned? Yes". BMJ: British Medical Journal.
  4. (2014). "Medical eponyms". Journal of Community Hospital Internal Medicine Perspectives.
  5. (30 June 2017). "Acantholysis or the Auspitz sign? A revelation of the life of Carl Heinrich Auspitz". Indian Journal of Dermatology, Venereology and Leprology.
  6. Kumar. (2010). "Robbin's Text book of Pathology". Elsevier.
  7. (June 1990). "Auspitz sign is not sensitive or specific for psoriasis". Journal of the American Academy of Dermatology.
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