Surf Wiki
Save to docs
general/ec-3-4-23

From Surf Wiki (app.surf) — the open knowledge base

Aspergillopepsin I

FieldValue
NameAspergillopepsin I
EC_number3.4.23.18
CAS_number9025-49-4

Aspergillopepsin I (, Aspergillus acid protease, Aspergillus acid proteinase, Aspergillus aspartic proteinase, Aspergillus awamori acid proteinase, Aspergillus carboxyl proteinase, carboxyl proteinase, Aspergillus kawachii aspartic proteinase, Aspergillus saitoi acid proteinase, pepsin-type aspartic proteinase, Aspergillus niger acid proteinase, sumizyme AP, proctase P, denapsin, denapsin XP 271, proctase) is an enzyme. This enzyme catalyses the following chemical reaction

: Hydrolysis of proteins with broad specificity. Generally favours hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk

This enzyme is found in a variety of Aspergillus species.

References

References

  1. (November 1972). "The site of diazoacetyl inhibitor attachment to acid proteinase of Aspergillus awamori--an analog of penicillopepsin and pepsin". Biochemical and Biophysical Research Communications.
  2. (August 1973). "Comparative specificity of microbial acid proteinases for synthetic peptides. 3. Relationship with their trypsinogen activating ability". Archives of Biochemistry and Biophysics.
  3. (April 1975). "Aspergillus oryzae acid proteinase. Purification and properties, and formation of pi-chymotrypsin". The Biochemical Journal.
  4. (November 1976). "The structure and function of acid proteases. VI. Effects of acid protease-specific inhibitors on the acid proteases from Aspergillus niger var. macrosporus". Journal of Biochemistry.
  5. (December 1977). "Purification of an acid proteinase from Aspergillus saitoi and determination of peptide bond specificity". Biochimica et Biophysica Acta (BBA) - Enzymology.
  6. (1976). "Aspergillopepsin F-A carboxylic proteinase from ''Aspergillus foetidus''". Bioorg. Khim..
  7. (1981). "Studies on the peptide bond specificity and the essential groups of an acid proteinase from Aspergillus fumigatus". The Italian Journal of Biochemistry.
  8. (1986). "The primary structure of aspergillopepsin A, aspartic proteinase from ''Aspergillus awamori''. IV. Amino acid sequence of the enzyme". Bioorg. Khim..
  9. (1986). "Purification and characterization of carboxyl proteinase from ''Aspergillus kawachii''". Agric. Biol. Chem..
  10. (1988). "Comparative study on the specificities of several fungal aspartic and acidic proteinases towards the tetradecapeptide of a renin substrate". Agric. Biol. Chem..
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-3.4.23
Want to explore this topic further?

Ask Mako anything about Aspergillopepsin I — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report