Apocrine nevus

Signs and symptoms

Apocrine nevi manifests as a persistent pedunculated or nodular skin-coloured axillary lump. Additionally, reports of them occurring on the face, scalp, chest, and inguinal area have been made. The majority of the time, apocrine nevi are asymptomatic, although some individuals describe minor pain, baldness, or in rare cases, leakage.

Causes

Apocrine nevi may be congenital. There have been reported associations with neurofibromatosis, epilepsy, and localized dermal hypoplasia, but these may be coincidental.

Diagnosis

According to histopathology, apocrine nevi are made up of several mature apocrine sweat glands grouped in lobules that invade the dermis and/or hypodermis and cause normal skin structures to be displaced. There may be some cystic dilatation of the lumina in these glands.

References

References

1. Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. {{ISBN. 0-07-138076-0.
2. (2012). "Pure Apocrine Nevus". Ovid Technologies (Wolters Kluwer Health).
3. (2006). "Syringocystadenoma papilliferum with extensive apocrine nevus". Wiley.
4. (1984). "The polymorphic apocrine nevus: A study of a unique tumor including carcinoembryonic antigen staining". Wiley.
5. (1987). "Piloleiomyoma Arising in an Organoid Nevus: A Case Report and Review of the Literature". Wiley.
6. (1988). "Apocrine nevus". Elsevier BV.
7. (1993). "APOCRINE NEVUS". International Journal of Dermatology.
8. (1993). "Apocrine nevus: light microscopic, immunohistochemical and ultrastructural studies of a case". Wiley.
9. (1995). "Congenital Apocrine Hamartoma: An Unusual Clinical Variant of Organoid Nevus with Apocrine Differentiation". Wiley.
10. (1976). "Fokale dermale hypoplasie mit apokrinen naevi und streifenförmiger anomalie der knochen". Archives of Dermatological Research.
11. (2011). "Pure Apocrine Nevus: Immunohistochemical Study of a New Case and Literature Review". Dermatology.