Antiene, New South Wales

| timezone-dst = AEDT | utc-dst = +11 | near-n = | near-ne = | near-e = | near-se = | near-s = | near-sw = | near-w = | near-nw = Antiene (also spelled Antienne) is a rural locality of the Muswellbrook Shire local government area in the Hunter Region of New South Wales, Australia. Named after County Antrim in Northern Ireland, the locality was registered as "Antiene" because the request was made in illegible handwriting.

The Main North railway line passes through the locality and is the site of a coal unloader, used to unload coal destined for the Bayswater and Liddell power stations. Until 2007, it was the site where the Main North railway became single track, the line has now been duplicated through to Muswellbrook to the north. A railway station opened at the site in 1890 and closed in 1975, no trace of this remains today.